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AI Predicts Brain Cancer Survivors within Eight-Months of Radiotherapy Using MRI Scan

By MedImaging International staff writers
Posted on 01 Feb 2024

Glioblastoma, a particularly challenging adult primary brain cancer to treat, has a low survival rate, with only one in four patients living beyond a year after diagnosis. Typically, patients undergo an eight-month course of chemotherapy following radiotherapy. Currently, regular and routine scanning is performed on patients with adult primary brain cancer to evaluate the effectiveness of chemotherapy. However, this process can result in some patients undergoing ineffective chemotherapy that not only fails to prolong life but also subjects them to detrimental side effects. Now, researchers have demonstrated that artificial intelligence (AI) can predict whether adult brain cancer patients will survive for more than eight months following radiotherapy. This groundbreaking use of AI in predicting patient outcomes could significantly guide clinicians in planning subsequent treatment stages and expedite referrals to potentially life-saving therapies. This marks the first instance of AI being used to distinguish between short-term and long-term survivors within eight months post-radiotherapy.

After radiotherapy, follow-up brain scan findings are often non-specific and oncologists cannot be certain whether a treatment is working or failing. A team from King’s College London developed a deep learning model to enhance the reliability and accuracy of predicting outcomes for patients with adult primary brain cancer. The AI was trained on tens of thousands of scans from a diverse range of brain cancer patients. Instead of trying to grapple with interpreting every non-specific follow-up brain scan, the AI can make an immediate and accurate prediction of which patients will not survive the next 8 months by simply looking at one routine scan after radiotherapy. This can empower clinicians and patients to make choices about their treatment. By providing an instant and accurate prediction from one routine MRI scan, the AI enables physicians to identify those patients unlikely to benefit from chemotherapy, allowing them to consider alternative treatments or enroll patients in clinical trials for experimental therapies.

“This is exciting and fundamental research for people living with a glioblastoma, for two reasons,” said Dr. Helen Bulbeck, Director of Services and Policy at brainstrust. “At its simplest level it demonstrates how AI can be used for patient benefit. More importantly however, it empowers patients and their caregivers to make choices about the clinical pathway and gives control back at a time when so much control has been lost. Patients will be able to make informed decisions about treatment choices and will be able to plan how they want to spend the time they have left so that they can live their best possible day, every day.”

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83 (28.133392333984): SELECT show_live FROM jos_com_show_setting LIMIT 1

84 (28.133392333984): SELECT show_live FROM jos_com_show_setting LIMIT 1

85 (28.133392333984): SELECT show_live FROM jos_com_show_setting LIMIT 1

86 (26.941299438477): SELECT show_live FROM jos_com_show_setting LIMIT 1

87 (27.179718017578): SELECT show_live FROM jos_com_show_setting LIMIT 1

88 (26.226043701172): SELECT show_live FROM jos_com_show_setting LIMIT 1

89 (28.133392333984): SELECT show_live FROM jos_com_show_setting LIMIT 1

90 (26.941299438477): SELECT show_live FROM jos_com_show_setting LIMIT 1

91 (26.941299438477): SELECT show_live FROM jos_com_show_setting LIMIT 1

92 (64.13459777832): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294800112 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294800112 AND published='1' LIMIT 1

93 (40.054321289062): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294800112 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294800112 AND published='1' LIMIT 1

94 (56.028366088867): SELECT dp.*, ch.title as channel, exp.name as author_name, exp.specialization as author_specialization, exp.images as author_photo FROM jos_deeppockets as dp LEFT JOIN jos_experts as exp ON exp.id = dp.author LEFT JOIN jos_deeppockets as ch ON dp.fid = ch.id WHERE 1=1 AND dp.cat=10 AND dp.id=294800112 AND (dp.type='deeppockets_item' OR dp.type='deeppockets_item_link') AND dp.published='1' LIMIT 1

95 (74.148178100586): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294800112 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294800112 AND published='1' LIMIT 1

96 (42.915344238281): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294800112 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294800112 AND published='1' LIMIT 1

97 (343.08433532715): SELECT dp.*, ch.title as channel, exp.name as author_name, exp.specialization as author_specialization, exp.images as author_photo FROM jos_deeppockets as dp LEFT JOIN jos_experts as exp ON exp.id = dp.author LEFT JOIN jos_deeppockets as ch ON dp.fid = ch.id WHERE 1=1 AND dp.id=294800112 AND (dp.type='deeppockets_item' OR dp.type='deeppockets_item_link') AND dp.published='1' LIMIT 1

98 (248.19374084473): SELECT dp.*, ch.title as channel, exp.name as author_name, exp.specialization as author_specialization, exp.images as author_photo FROM jos_deeppockets as dp LEFT JOIN jos_experts as exp ON exp.id = dp.author LEFT JOIN jos_deeppockets as ch ON dp.fid = ch.id WHERE 1=1 AND dp.id=294800105 AND (dp.type='deeppockets_item' OR dp.type='deeppockets_item_link') AND dp.published='1' LIMIT 1

99 (611.0668182373): SELECT dp.name, dp.id, dp2.name as channel, ex.name as author_name, ex.specialization, ex.images FROM jos_deeppockets as dp LEFT JOIN jos_experts as ex ON ex.id = dp.author LEFT JOIN jos_deeppockets as dp2 ON dp2.id = dp.fid WHERE dp.author != 0 AND dp.cat = 10 AND dp.published = 1 AND ( (dp.fid = 294743300) OR (dp.fid = 294743301) OR (dp.fid = 294743302) OR (dp.fid = 294743303) OR (dp.fid = 294743304) OR (dp.fid = 294743305) OR (dp.fid = 294743306) OR (dp.fid = 294743307) OR (dp.fid = 294743308) OR (dp.fid = 294743309) OR (dp.fid = 294743310) ) ORDER BY RAND() LIMIT 1

100 (385.04600524902): SELECT dp.name, dp.id, dp2.name as channel, ex.name as author_name, ex.specialization, ex.images FROM jos_deeppockets as dp LEFT JOIN jos_experts as ex ON ex.id = dp.author LEFT JOIN jos_deeppockets as dp2 ON dp2.id = dp.fid WHERE dp.author != 0 AND dp.cat = 10 AND dp.published = 1 AND ( (dp.fid = 294743300) OR (dp.fid = 294743301) OR (dp.fid = 294743302) OR (dp.fid = 294743303) OR (dp.fid = 294743304) OR (dp.fid = 294743305) OR (dp.fid = 294743306) OR (dp.fid = 294743307) OR (dp.fid = 294743308) OR (dp.fid = 294743309) OR (dp.fid = 294743310) ) ORDER BY RAND() LIMIT 1

101 (65.803527832031): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294800112 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294800112 AND published='1' LIMIT 1

102 (41.007995605469): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294800112 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294800112 AND published='1' LIMIT 1

103 (114.91775512695): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294800112 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294800112 AND published='1' LIMIT 1

104 (38.862228393555): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294800112 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294800112 AND published='1' LIMIT 1

105 (92.983245849609): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294800112 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294800112 AND published='1' LIMIT 1

106 (51.021575927734): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294800112 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294800112 AND published='1' LIMIT 1

107 (216.00723266602): SELECT * FROM trending_articles WHERE `journal_id` = 10 AND `timestamp` <= NOW() + INTERVAL 7 DAY ORDER BY `order`

108 (!!!!! 127543.21098328): SELECT * FROM jos_deeppockets WHERE jos_deeppockets.cat = 10 AND jos_deeppockets.type = 'deeppockets_item' AND jos_deeppockets.published = 1 AND jos_deeppockets.created + INTERVAL 14 DAY >= NOW() ORDER BY jos_deeppockets.hits DESC LIMIT 7

109 (!!!!! 4553.0796051025): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294800112 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294800112 AND published='1' LIMIT 1

110 (83.92333984375): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294800112 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294800112 AND published='1' LIMIT 1

111 (416.04042053223): SELECT fid FROM jos_deeppockets WHERE cat=10 AND id=294800112 AND type='deeppockets_item' AND published='1' union SELECT fid FROM jos_deeppockets_archive WHERE cat=10 AND id=294800112 AND type='deeppockets_item' AND published='1' LIMIT 1

112 (!!!!! 1635773.897171): ( SELECT dp.id, dp.name, dp.title, dp.video, dp.video_source, dp.created FROM jos_deeppockets AS dp WHERE dp.video != '' AND dp.video_source != '' AND dp.cat = 10 AND dp.published = 1 AND dp.type != 'deeppockets_item_link' ORDER BY created DESC LIMIT 3 ) UNION ( SELECT dpa.id, dpa.name, dpa.title, dpa.video, dpa.video_source, dpa.created FROM jos_deeppockets_archive AS dpa WHERE dpa.video != '' AND dpa.video_source != '' AND dpa.cat = 10 AND dpa.published = 1 AND dpa.type != 'deeppockets_item_link' ORDER BY created DESC LIMIT 3 ) ORDER BY created DESC LIMIT 3

113 (!!!!! 1487811.088562): ( SELECT dp.id, dp.name, dp.title, dp.video, dp.video_source, dp.created FROM jos_deeppockets AS dp WHERE dp.video != '' AND dp.video_source != '' AND dp.cat = 10 AND dp.published = 1 AND dp.type != 'deeppockets_item_link' ORDER BY created DESC LIMIT 3 ) UNION ( SELECT dpa.id, dpa.name, dpa.title, dpa.video, dpa.video_source, dpa.created FROM jos_deeppockets_archive AS dpa WHERE dpa.video != '' AND dpa.video_source != '' AND dpa.cat = 10 AND dpa.published = 1 AND dpa.type != 'deeppockets_item_link' ORDER BY created DESC LIMIT 3 ) ORDER BY created DESC LIMIT 3

114 (!!!!! 1259.8037719727): SELECT dp.id, dp.name, dp.title, dp.video, dp.video_source, dp.created FROM jos_deeppockets AS dp WHERE dp.id = 294800513 LIMIT 1

115 (56.982040405273): SELECT dp.id, dp.name, dp.title, dp.video, dp.video_source, dp.created FROM jos_deeppockets AS dp WHERE dp.id = 294800513 LIMIT 1

116 (330.92498779297): SELECT dp.id, dp.name, dp.title, dp.video, dp.video_source, dp.created FROM jos_deeppockets AS dp WHERE dp.id = 294800359 LIMIT 1

117 (87.976455688477): SELECT dp.id, dp.name, dp.title, dp.video, dp.video_source, dp.created FROM jos_deeppockets AS dp WHERE dp.id = 294800359 LIMIT 1

118 (246.04797363281): SELECT dp.id, dp.name, dp.title, dp.video, dp.video_source, dp.created FROM jos_deeppockets AS dp WHERE dp.id = 294800361 LIMIT 1

119 (35.04753112793): SELECT dp.id, dp.name, dp.title, dp.video, dp.video_source, dp.created FROM jos_deeppockets AS dp WHERE dp.id = 294800361 LIMIT 1

120 (392.91381835938): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294800112 AND (type='deeppockets_item' OR type='deeppockets_item_link') AND published='1' LIMIT 1

121 (170.94612121582): SELECT name FROM jos_deeppockets WHERE id=213

122 (30.994415283203): SELECT name FROM jos_deeppockets WHERE id=213

123 (437.97492980957): SELECT *, DATE_FORMAT(publish_up,'%d %b %Y') AS date_publish_up, DATE_FORMAT(publish_down,'%d %b %Y') AS date_publish_down FROM jos_events WHERE state=1 AND publish_up > NOW() and extra_info REGEXP '((;)|(^))213((;)|($))' AND catid IN (0,110) ORDER BY publish_up ASC LIMIT 3

124 (355.95893859863): SELECT *, DATE_FORMAT(publish_up,'%d %b %Y') AS date_publish_up, DATE_FORMAT(publish_down,'%d %b %Y') AS date_publish_down FROM jos_events WHERE state=1 AND publish_up > NOW() and extra_info REGEXP '((;)|(^))213((;)|($))' AND catid IN (0,110) ORDER BY publish_up ASC LIMIT 3

125 (941.03813171387): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294800112 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294800112 AND published='1' LIMIT 1

126 (54.121017456055): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294800112 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294800112 AND published='1' LIMIT 1

127 (!!!!! 7292.9859161377): TRUNCATE TABLE jos_trademed_module

128 (475.88348388672): SELECT dp.*, ch.title as channel, exp.name as author_name, exp.specialization as author_specialization, exp.images as author_photo FROM jos_deeppockets as dp LEFT JOIN jos_experts as exp ON exp.id = dp.author LEFT JOIN jos_deeppockets as ch ON dp.fid = ch.id WHERE 1=1 AND dp.cat=10 AND dp.id=294800112 AND (dp.type='deeppockets_item' OR dp.type='deeppockets_item_link') AND dp.published='1' LIMIT 1

129 (503.0632019043): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294800112 AND (type='deeppockets_item' OR type='deeppockets_item_link') AND published='1' LIMIT 1

130 (55.074691772461): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294800112 AND (type='deeppockets_item' OR type='deeppockets_item_link') AND published='1' LIMIT 1

131 (48.160552978516): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294800112 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294800112 AND published='1' LIMIT 1

132 (33.855438232422): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294800112 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294800112 AND published='1' LIMIT 1

133 (!!!!! 1029.9682617188): SELECT jos_item.* FROM jos_item INNER JOIN jos_number ON jos_item.numberID=jos_number.id WHERE 1=1 AND (jos_item.imgMini<>'') AND jos_item.type='L' AND jos_item.numberID= ( SELECT jos_number.id FROM jos_number WHERE jos_number.journalID IN (10) and jos_number.id in (select distinct jos_number.id from jos_number join jos_item on jos_item.numberid=jos_number.id where jos_item.type='P') ORDER BY (CONVERT(SUBSTRING(issue,1,2),SIGNED) + (CONVERT(SUBSTRING(issue,3,2),SIGNED)*100)) DESC LIMIT 0,1 ) ORDER BY RAND() DESC LIMIT 6

134 (47.922134399414): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294800112 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294800112 AND published='1' LIMIT 1

135 (39.100646972656): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294800112 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294800112 AND published='1' LIMIT 1

136 (!!!!! 1062.8700256348): SELECT fid FROM jos_deeppockets WHERE cat=10 AND id=294800112 AND type='deeppockets_item' AND published='1' union SELECT fid FROM jos_deeppockets_archive WHERE cat=10 AND id=294800112 AND type='deeppockets_item' AND published='1' LIMIT 1

137 (416.99409484863): select distinct links.* from jos_textlinks links join jos_textlinks_placement placement on links.id=placement.link_id where journal_id=(10) and (channel_id=0 or channel_id is null)

138 (33.140182495117): select distinct links.* from jos_textlinks links join jos_textlinks_placement placement on links.id=placement.link_id where journal_id=(10) and (channel_id=0 or channel_id is null)

139 (31.232833862305): SELECT livesite FROM jos_dp_categories WHERE id=10 AND published='1' LIMIT 1

140 (113.01040649414): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294800112 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294800112 AND published='1' LIMIT 1

141 (95.844268798828): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294800112 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294800112 AND published='1' LIMIT 1

142 (130.89179992676): select jos_twitters.link from jos_twitters where cat=10

143 (30.994415283203): select jos_facebook.link from jos_facebook where cat=10

144 (26.941299438477): select jos_google_plus.link from jos_google_plus where cat=10

145 (27.179718017578): select jos_linkedin.link from jos_linkedin where cat=10

146 (227.92816162109): update jos_bannersmanager_banner set impmade=impmade+1 where id in(14615,14202,14203)

147 (!!!!! 2810.9550476074): insert into jos_banners_delta values (14615,'2025-04-29 17:19:50','3.144.254.237','view'),(14202,'2025-04-29 17:19:50','3.144.254.237','view'),(14203,'2025-04-29 17:19:50','3.144.254.237','view')

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