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New Hand-Held OCT Device to Simplify Early Detection of Retinal Disease

By MedImaging International staff writers
Posted on 31 Dec 2013
A novel hand-held optical device quickly scans a patient’s entire retina and so could aid in detecting early signs of a host of retinal diseases, including diabetic retinopathy, glaucoma, and macular degeneration.

A team at the Massachusetts Institute of Technology (MIT; Cambridge, MA, USA) describes their new ophthalmic-screening instrument in a report by Lu, C.D. et al., published by The Optical Society (Washington DC, USA), December 20, 2013, in the journal Biomedical Optics Express. Although others have created hand-held devices using similar technology, the new design is the first to combine cutting-edge technologies such as ultrahigh-speed 3D imaging, a tiny micro-electromechanical systems (MEMS) mirror for scanning, and a technique to correct for unintentional movement by the patient. These innovations should allow clinicians to collect comprehensive data with just one measurement.

Many eye diseases should be detected and treated long before any visual symptoms arise, but few people visit eye specialists regularly. The MIT group, in collaboration with the University of Erlangen and Praevium/Thorlabs, has developed this portable instrument to improve public access to eye care. "Hand-held instruments can enable screening a wider population outside the traditional points of care," said Prof. James Fujimoto, MIT. They can be used at a primary-care physician's office or even in the developing world.

The instrument uses optical coherence tomography (OCT), which sends beams of infrared light into the eye and onto the retina. Echoes of this light return to the instrument, which uses interferometry to measure changes in the time delay and magnitude of the returning light echoes, revealing the cross-sectional tissue structure of the retina, similar to radar or ultrasound imaging. Tabletop OCT imagers have become a standard of care in ophthalmology, and current generation hand-held scanners are used for imaging infants and monitoring retinal surgery. The MIT group turned a typically large instrument into a portable size by using a MEMS mirror to scan the OCT imaging beam. The new device can acquire images comparable in quality to the conventional tabletop OCT instruments used by ophthalmologists.

To deal with the motion instability of a hand-held device, the instrument takes multiple 3D images at high speeds, scanning one particular volume of the eye many times but with different scanning directions. This makes it possible to correct for distortions due to motion of the operator’s hand or the subject’s eye.

The next step, said Prof. Fujimoto, is to evaluate the technology in clinical settings; however, the device is still expensive. "The hand-held platform allows the diagnosis or screening to be performed in a much wider range of settings,” said Prof. Fujimoto. He envisions that in the future hand-held OCT technology can be used in many other medical specialties beyond ophthalmology, such as in applications ranging from surgical guidance to military medicine.

Related Links:
Massachusetts Institute of Technology
The Optical Society



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48
(27.179718017578): SELECT
				dp.id,
				dp.name,
				dp.title,
				dp.video,
				dp.video_source,
				dp.created

			FROM
				jos_deeppockets AS dp

			WHERE
				dp.id = 294749934

			LIMIT 1
49
(27.179718017578): SELECT
				dp.id,
				dp.name,
				dp.title,
				dp.video,
				dp.video_source,
				dp.created

			FROM
				jos_deeppockets_archive AS dp

			WHERE
				dp.id = 294749934

			LIMIT 1
50
(28.133392333984): SELECT
				dp.id,
				dp.name,
				dp.title,
				dp.video,
				dp.video_source,
				dp.created

			FROM
				jos_deeppockets_archive AS dp

			WHERE
				dp.id = 294749934

			LIMIT 1
51
(45.061111450195): select journal.name,journal.id,dpcat.livesite,journal.code
				from jos_dp_categories dpcat
				join jos_journal journal
				on journal.id=dpcat.journalid
				where dpcat.id=10
52
(95.844268798828): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294749934 AND published='1'
				union
		SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294749934 AND published='1'
		LIMIT 1
53
(52.928924560547): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294749934 AND published='1'
				union
		SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294749934 AND published='1'
		LIMIT 1
54
(65.088272094727): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294749934 AND published='1'
				union
		SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294749934 AND published='1'
		LIMIT 1
55
(48.87580871582): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294749934 AND published='1'
				union
		SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294749934 AND published='1'
		LIMIT 1
56
(55.074691772461): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294749934 AND published='1'
				union
		SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294749934 AND published='1'
		LIMIT 1
57
(46.968460083008): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294749934 AND published='1'
				union
		SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294749934 AND published='1'
		LIMIT 1
58
(82.015991210938): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294749934 AND published='1'
				union
		SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294749934 AND published='1'
		LIMIT 1
59
(53.882598876953): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294749934 AND published='1'
				union
		SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294749934 AND published='1'
		LIMIT 1
60
(185.96649169922): SELECT name FROM jos_deeppockets WHERE id=294749934 LIMIT 1
61
(113.96408081055): SELECT name FROM jos_deeppockets_archive WHERE id=294749934 LIMIT 1
62
(158.07151794434): SELECT a.*
 FROM jos_components AS a
 WHERE ( a.admin_menu_link = 'option=com_syndicate' OR a.admin_menu_link = 'option=com_syndicate&hidemainmenu=1' )
 AND a.option = 'com_syndicate'
63
(60.081481933594): SELECT dp.*, ch.title as channel, exp.name as author_name, exp.specialization as author_specialization, exp.images as author_photo FROM jos_deeppockets as dp
							LEFT JOIN jos_experts as exp
							ON exp.id = dp.author
							LEFT JOIN jos_deeppockets as ch
							ON dp.fid = ch.id
							WHERE 1=1
							 AND dp.cat=10 
							AND dp.id=294749934
							AND (dp.type='deeppockets_item' OR dp.type='deeppockets_item_link')
							AND dp.published='1' LIMIT 1
64
(456.09474182129): SELECT dp.*, ch.title as channel, exp.name as author_name, exp.specialization as author_specialization, exp.images as author_photo FROM jos_deeppockets_archive as dp
								LEFT JOIN jos_experts as exp
								ON exp.id = dp.author
								LEFT JOIN jos_deeppockets as ch
								ON dp.fid = ch.id
								WHERE 1=1
								 AND dp.cat=10 
								AND dp.id=294749934
								AND (dp.type='deeppockets_item' OR dp.type='deeppockets_item_link')
								AND dp.published='1' LIMIT 1
65
(!!!!! 1340.1508331299): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294749934 AND published='1'
				union
		SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294749934 AND published='1'
		LIMIT 1
66
(74.863433837891): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294749934 AND published='1'
				union
		SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294749934 AND published='1'
		LIMIT 1
67
(185.01281738281): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294749934 AND published='1'
				union
		SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294749934 AND published='1'
		LIMIT 1
68
(136.8522644043): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294749934 AND published='1'
				union
		SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294749934 AND published='1'
		LIMIT 1
69
(!!!!! 5184.1735839844): select cover from jos_number
where journalid in (5) and cover is not null
order by left(issue,2)+right(issue,2)*12 desc limit 1
70
(540.01808166504): SELECT fid FROM jos_deeppockets WHERE id=294749934 AND published='1' union SELECT fid FROM jos_deeppockets_archive WHERE id=294749934 AND published='1'  LIMIT 1
71
(128.03077697754): SELECT id,name,sponsor_text
                    FROM jos_deeppockets dp
					left outer join jos_channel_sponsor cs
					on dp.id=cs.fid
                    WHERE cat=10
                    AND TYPE='file_folder'
                    AND published=1
                    AND id=215
                    ORDER BY `ordering`
72
(46.014785766602): select jos_twitters.link from jos_twitters where cat=10
73
(28.133392333984): select jos_facebook.link from jos_facebook where cat=10
74
(27.179718017578): select jos_google_plus.link from jos_google_plus where cat=10
75
(25.033950805664): select jos_linkedin.link from jos_linkedin where cat=10
76
(29.087066650391): SELECT fid FROM jos_deeppockets WHERE id=294749934 AND published='1' union SELECT fid FROM jos_deeppockets_archive WHERE id=294749934 AND published='1'  LIMIT 1
77
(27.894973754883): SELECT id,name,sponsor_text
                    FROM jos_deeppockets dp
					left outer join jos_channel_sponsor cs
					on dp.id=cs.fid
                    WHERE cat=10
                    AND TYPE='file_folder'
                    AND published=1
                    AND id=215
                    ORDER BY `ordering`
78
(172.13821411133): SELECT fid FROM jos_deeppockets
								WHERE cat=10
								AND id=294749934
								AND (type='deeppockets_item' OR type='deeppockets_item_link') 
								AND published='1' 
								LIMIT 1
79
(130.89179992676): SELECT fid FROM jos_deeppockets_archive WHERE cat=10 AND id=294749934 AND (type='deeppockets_item' OR type='deeppockets_item_link') AND published='1' LIMIT 1
80
(41.007995605469): SELECT id,name,title
 FROM jos_deeppockets WHERE cat=10 AND TYPE='file_folder' AND published=1
			AND id != 294743300
			AND id != 294743301
			AND id != 294743302
			AND id != 294743303
			AND id != 294743304
			AND id != 294743305
			AND id != 294743306
			AND id != 294743307
			AND id != 294743308
			AND id != 294743309
			AND id != 294743310
			AND metakey != 'aacc'
		ORDER BY `ordering`
81
(46.014785766602): SELECT show_live FROM jos_com_show_setting LIMIT 1
82
(29.087066650391): SELECT show_live FROM jos_com_show_setting LIMIT 1
83
(25.033950805664): SELECT show_live FROM jos_com_show_setting LIMIT 1
84
(25.033950805664): SELECT show_live FROM jos_com_show_setting LIMIT 1
85
(25.033950805664): SELECT show_live FROM jos_com_show_setting LIMIT 1
86
(23.841857910156): SELECT show_live FROM jos_com_show_setting LIMIT 1
87
(24.795532226562): SELECT show_live FROM jos_com_show_setting LIMIT 1
88
(25.033950805664): SELECT show_live FROM jos_com_show_setting LIMIT 1
89
(25.033950805664): SELECT show_live FROM jos_com_show_setting LIMIT 1
90
(25.033950805664): SELECT show_live FROM jos_com_show_setting LIMIT 1
91
(25.033950805664): SELECT show_live FROM jos_com_show_setting LIMIT 1
92
(25.033950805664): SELECT show_live FROM jos_com_show_setting LIMIT 1
93
(24.080276489258): SELECT show_live FROM jos_com_show_setting LIMIT 1
94
(24.795532226562): SELECT show_live FROM jos_com_show_setting LIMIT 1
95
(37.908554077148): SELECT fid FROM jos_deeppockets
								WHERE cat=10
								AND id=294749934
								AND (type='deeppockets_item' OR type='deeppockets_item_link') 
								AND published='1' 
								LIMIT 1
96
(26.941299438477): SELECT fid FROM jos_deeppockets_archive WHERE cat=10 AND id=294749934 AND (type='deeppockets_item' OR type='deeppockets_item_link') AND published='1' LIMIT 1
97
(30.994415283203): SELECT id,name,title
 FROM jos_deeppockets WHERE cat=10 AND TYPE='file_folder' AND published=1
			AND id != 294743300
			AND id != 294743301
			AND id != 294743302
			AND id != 294743303
			AND id != 294743304
			AND id != 294743305
			AND id != 294743306
			AND id != 294743307
			AND id != 294743308
			AND id != 294743309
			AND id != 294743310
			AND metakey != 'aacc'
		ORDER BY `ordering`
98
(50.067901611328): SELECT show_live FROM jos_com_show_setting LIMIT 1
99
(28.133392333984): SELECT show_live FROM jos_com_show_setting LIMIT 1
100
(25.033950805664): SELECT show_live FROM jos_com_show_setting LIMIT 1
101
(25.98762512207): SELECT show_live FROM jos_com_show_setting LIMIT 1
102
(25.033950805664): SELECT show_live FROM jos_com_show_setting LIMIT 1
103
(25.033950805664): SELECT show_live FROM jos_com_show_setting LIMIT 1
104
(24.080276489258): SELECT show_live FROM jos_com_show_setting LIMIT 1
105
(24.795532226562): SELECT show_live FROM jos_com_show_setting LIMIT 1
106
(24.080276489258): SELECT show_live FROM jos_com_show_setting LIMIT 1
107
(25.033950805664): SELECT show_live FROM jos_com_show_setting LIMIT 1
108
(25.033950805664): SELECT show_live FROM jos_com_show_setting LIMIT 1
109
(25.033950805664): SELECT show_live FROM jos_com_show_setting LIMIT 1
110
(25.033950805664): SELECT show_live FROM jos_com_show_setting LIMIT 1
111
(25.033950805664): SELECT show_live FROM jos_com_show_setting LIMIT 1
112
(!!!!! 1769.0658569336): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294749934 AND published='1'
				union
		SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294749934 AND published='1'
		LIMIT 1
113
(70.095062255859): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294749934 AND published='1'
				union
		SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294749934 AND published='1'
		LIMIT 1
114
(52.928924560547): SELECT dp.*, ch.title as channel, exp.name as author_name, exp.specialization as author_specialization, exp.images as author_photo FROM jos_deeppockets as dp
							LEFT JOIN jos_experts as exp
							ON exp.id = dp.author
							LEFT JOIN jos_deeppockets as ch
							ON dp.fid = ch.id
							WHERE 1=1
							 AND dp.cat=10 
							AND dp.id=294749934
							AND (dp.type='deeppockets_item' OR dp.type='deeppockets_item_link')
							AND dp.published='1' LIMIT 1
115
(46.014785766602): SELECT dp.*, ch.title as channel, exp.name as author_name, exp.specialization as author_specialization, exp.images as author_photo FROM jos_deeppockets_archive as dp
								LEFT JOIN jos_experts as exp
								ON exp.id = dp.author
								LEFT JOIN jos_deeppockets as ch
								ON dp.fid = ch.id
								WHERE 1=1
								 AND dp.cat=10 
								AND dp.id=294749934
								AND (dp.type='deeppockets_item' OR dp.type='deeppockets_item_link')
								AND dp.published='1' LIMIT 1
116
(61.03515625): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294749934 AND published='1'
				union
		SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294749934 AND published='1'
		LIMIT 1
117
(42.915344238281): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294749934 AND published='1'
				union
		SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294749934 AND published='1'
		LIMIT 1
118
(43.869018554688): SELECT dp.*, ch.title as channel, exp.name as author_name, exp.specialization as author_specialization, exp.images as author_photo FROM jos_deeppockets as dp
							LEFT JOIN jos_experts as exp
							ON exp.id = dp.author
							LEFT JOIN jos_deeppockets as ch
							ON dp.fid = ch.id
							WHERE 1=1
							
							AND dp.id=294749934
							AND (dp.type='deeppockets_item' OR dp.type='deeppockets_item_link')
							AND dp.published='1' LIMIT 1
119
(502.8247833252): SELECT dp.*, ch.title as channel, exp.name as author_name, exp.specialization as author_specialization, exp.images as author_photo FROM jos_deeppockets_archive as dp
								LEFT JOIN jos_experts as exp
								ON exp.id = dp.author
								LEFT JOIN jos_deeppockets as ch
								ON dp.fid = ch.id
								WHERE 1=1
								
								AND dp.id=294749934
								AND (dp.type='deeppockets_item' OR dp.type='deeppockets_item_link')
								AND dp.published='1' LIMIT 1
120
(648.02169799805): SELECT dp.name, dp.id, dp2.name as channel, ex.name as author_name, ex.specialization, ex.images FROM jos_deeppockets as dp
							LEFT JOIN jos_experts as ex
							ON ex.id = dp.author
							LEFT JOIN jos_deeppockets as dp2
							ON dp2.id = dp.fid
							WHERE dp.author != 0
							AND dp.cat = 10
							AND dp.published = 1
							AND (
								(dp.fid = 294743300)
								OR (dp.fid = 294743301)
								OR (dp.fid = 294743302)
								OR (dp.fid = 294743303)
								OR (dp.fid = 294743304)
								OR (dp.fid = 294743305)
								OR (dp.fid = 294743306)
								OR (dp.fid = 294743307)
								OR (dp.fid = 294743308)
								OR (dp.fid = 294743309)
								OR (dp.fid = 294743310)
								)
							ORDER BY RAND()
							LIMIT 1
121
(411.9873046875): SELECT dp.name, dp.id, dp2.name as channel, ex.name as author_name, ex.specialization, ex.images FROM jos_deeppockets as dp
							LEFT JOIN jos_experts as ex
							ON ex.id = dp.author
							LEFT JOIN jos_deeppockets as dp2
							ON dp2.id = dp.fid
							WHERE dp.author != 0
							AND dp.cat = 10
							AND dp.published = 1
							AND (
								(dp.fid = 294743300)
								OR (dp.fid = 294743301)
								OR (dp.fid = 294743302)
								OR (dp.fid = 294743303)
								OR (dp.fid = 294743304)
								OR (dp.fid = 294743305)
								OR (dp.fid = 294743306)
								OR (dp.fid = 294743307)
								OR (dp.fid = 294743308)
								OR (dp.fid = 294743309)
								OR (dp.fid = 294743310)
								)
							ORDER BY RAND()
							LIMIT 1
122
(76.055526733398): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294749934 AND published='1'
				union
		SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294749934 AND published='1'
		LIMIT 1
123
(75.817108154297): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294749934 AND published='1'
				union
		SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294749934 AND published='1'
		LIMIT 1
124
(43.869018554688): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294749934 AND published='1'
				union
		SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294749934 AND published='1'
		LIMIT 1
125
(39.100646972656): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294749934 AND published='1'
				union
		SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294749934 AND published='1'
		LIMIT 1
126
(43.153762817383): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294749934 AND published='1'
				union
		SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294749934 AND published='1'
		LIMIT 1
127
(44.107437133789): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294749934 AND published='1'
				union
		SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294749934 AND published='1'
		LIMIT 1
128
(281.09550476074): SELECT * FROM trending_articles WHERE `journal_id` = 10 AND `timestamp` <= NOW() + INTERVAL 7 DAY ORDER BY `order`
129
(!!!!! 120958.08982849): SELECT
				*
			FROM
				jos_deeppockets
			WHERE
				jos_deeppockets.cat = 10
			AND
				jos_deeppockets.type = 'deeppockets_item'
			AND
				jos_deeppockets.published = 1
			AND
				jos_deeppockets.created + INTERVAL 14 DAY >= NOW()
			ORDER BY
				jos_deeppockets.hits DESC
			LIMIT
				7
130
(785.11238098145): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294749934 AND published='1'
				union
		SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294749934 AND published='1'
		LIMIT 1
131
(514.98413085938): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294749934 AND published='1'
				union
		SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294749934 AND published='1'
		LIMIT 1
132
(!!!!! 3396.0342407227): SELECT fid FROM jos_deeppockets WHERE cat=10 AND id=294749934 AND type='deeppockets_item' AND published='1' union SELECT fid FROM jos_deeppockets_archive WHERE cat=10 AND id=294749934 AND type='deeppockets_item' AND published='1'  LIMIT 1
133
(!!!!! 647655.01022339): (
				SELECT
					dp.id,
					dp.name,
					dp.title,
					dp.video,
					dp.video_source,
					dp.created

				FROM
					jos_deeppockets AS dp

				WHERE
					dp.video != ''
				AND
					dp.video_source != ''
				AND
					dp.cat = 10
				AND
					dp.published = 1
				AND
					dp.type != 'deeppockets_item_link'

				

				ORDER BY
					created DESC

				LIMIT
					3
			)
			UNION
			(
				SELECT
					dpa.id,
					dpa.name,
					dpa.title,
					dpa.video,
					dpa.video_source,
					dpa.created

				FROM
					jos_deeppockets_archive AS dpa

				WHERE
					dpa.video != ''
				AND
					dpa.video_source != ''
				AND
					dpa.cat = 10
				AND
					dpa.published = 1
				AND
					dpa.type != 'deeppockets_item_link'

				

				ORDER BY
					created DESC

				LIMIT
					3
			)
			ORDER BY
				created DESC

			LIMIT
				3
134
(!!!!! 1849547.1477509): (
				SELECT
					dp.id,
					dp.name,
					dp.title,
					dp.video,
					dp.video_source,
					dp.created

				FROM
					jos_deeppockets AS dp

				WHERE
					dp.video != ''
				AND
					dp.video_source != ''
				AND
					dp.cat = 10
				AND
					dp.published = 1
				AND
					dp.type != 'deeppockets_item_link'

				

				ORDER BY
					created DESC

				LIMIT
					3
			)
			UNION
			(
				SELECT
					dpa.id,
					dpa.name,
					dpa.title,
					dpa.video,
					dpa.video_source,
					dpa.created

				FROM
					jos_deeppockets_archive AS dpa

				WHERE
					dpa.video != ''
				AND
					dpa.video_source != ''
				AND
					dpa.cat = 10
				AND
					dpa.published = 1
				AND
					dpa.type != 'deeppockets_item_link'

				

				ORDER BY
					created DESC

				LIMIT
					3
			)
			ORDER BY
				created DESC

			LIMIT
				3
135
(!!!!! 6598.949432373): SELECT
				dp.id,
				dp.name,
				dp.title,
				dp.video,
				dp.video_source,
				dp.created

			FROM
				jos_deeppockets AS dp

			WHERE
				dp.id = 294800513

			LIMIT 1
136
(!!!!! 13077.974319458): SELECT
				dp.id,
				dp.name,
				dp.title,
				dp.video,
				dp.video_source,
				dp.created

			FROM
				jos_deeppockets AS dp

			WHERE
				dp.id = 294800513

			LIMIT 1
137
(!!!!! 11284.112930298): SELECT
				dp.id,
				dp.name,
				dp.title,
				dp.video,
				dp.video_source,
				dp.created

			FROM
				jos_deeppockets AS dp

			WHERE
				dp.id = 294800359

			LIMIT 1
138
(!!!!! 6185.0547790527): SELECT
				dp.id,
				dp.name,
				dp.title,
				dp.video,
				dp.video_source,
				dp.created

			FROM
				jos_deeppockets AS dp

			WHERE
				dp.id = 294800359

			LIMIT 1
139
(305.8910369873): SELECT
				dp.id,
				dp.name,
				dp.title,
				dp.video,
				dp.video_source,
				dp.created

			FROM
				jos_deeppockets AS dp

			WHERE
				dp.id = 294800361

			LIMIT 1
140
(617.98095703125): SELECT
				dp.id,
				dp.name,
				dp.title,
				dp.video,
				dp.video_source,
				dp.created

			FROM
				jos_deeppockets AS dp

			WHERE
				dp.id = 294800361

			LIMIT 1
141
(321.1498260498): SELECT *
                            FROM jos_deeppockets
                            WHERE 1=1 
                              AND id=294749934
                              AND (type='deeppockets_item' OR type='deeppockets_item_link')
                              AND published='1'
                            LIMIT 1
142
(292.06275939941): SELECT *
                            FROM jos_deeppockets_archive
                            WHERE 1=1 
                              AND id=294749934
                              AND (type='deeppockets_item' OR type='deeppockets_item_link')
                              AND published='1'
                            LIMIT 1
143
(46.014785766602): SELECT name FROM jos_deeppockets WHERE id=215
144
(!!!!! 1669.8837280273): SELECT name FROM jos_deeppockets WHERE id=215
145
(504.0168762207): SELECT *,
    DATE_FORMAT(publish_up,'%d %b %Y') AS date_publish_up,
    DATE_FORMAT(publish_down,'%d %b %Y') AS date_publish_down
    FROM jos_events
    WHERE state=1
    AND publish_up > NOW()
    and extra_info REGEXP '((;)|(^))215((;)|($))' AND catid IN (0,110) 
    ORDER BY publish_up ASC LIMIT 3
146
(365.9725189209): SELECT *,
    DATE_FORMAT(publish_up,'%d %b %Y') AS date_publish_up,
    DATE_FORMAT(publish_down,'%d %b %Y') AS date_publish_down
    FROM jos_events
    WHERE state=1
    AND publish_up > NOW()
    and extra_info REGEXP '((;)|(^))215((;)|($))' AND catid IN (0,110) 
    ORDER BY publish_up ASC LIMIT 3
147
(!!!!! 1346.1112976074): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294749934 AND published='1'
				union
		SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294749934 AND published='1'
		LIMIT 1
148
(76.770782470703): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294749934 AND published='1'
				union
		SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294749934 AND published='1'
		LIMIT 1
149
(!!!!! 9855.9856414795): TRUNCATE TABLE jos_trademed_module
150
(!!!!! 1224.0409851074): SELECT dp.*, ch.title as channel, exp.name as author_name, exp.specialization as author_specialization, exp.images as author_photo FROM jos_deeppockets as dp
							LEFT JOIN jos_experts as exp
							ON exp.id = dp.author
							LEFT JOIN jos_deeppockets as ch
							ON dp.fid = ch.id
							WHERE 1=1
							 AND dp.cat=10 
							AND dp.id=294749934
							AND (dp.type='deeppockets_item' OR dp.type='deeppockets_item_link')
							AND dp.published='1' LIMIT 1
151
(575.06561279297): SELECT dp.*, ch.title as channel, exp.name as author_name, exp.specialization as author_specialization, exp.images as author_photo FROM jos_deeppockets_archive as dp
								LEFT JOIN jos_experts as exp
								ON exp.id = dp.author
								LEFT JOIN jos_deeppockets as ch
								ON dp.fid = ch.id
								WHERE 1=1
								 AND dp.cat=10 
								AND dp.id=294749934
								AND (dp.type='deeppockets_item' OR dp.type='deeppockets_item_link')
								AND dp.published='1' LIMIT 1
152
(411.03363037109): SELECT *
   FROM jos_deeppockets
   WHERE 1=1 
   AND id=294749934
   AND (type='deeppockets_item' OR type='deeppockets_item_link') AND published='1' LIMIT 1
153
(56.028366088867): SELECT *
   FROM jos_deeppockets
   WHERE 1=1 
   AND id=294749934
   AND (type='deeppockets_item' OR type='deeppockets_item_link') AND published='1' LIMIT 1
154
(66.041946411133): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294749934 AND published='1'
				union
		SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294749934 AND published='1'
		LIMIT 1
155
(51.021575927734): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294749934 AND published='1'
				union
		SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294749934 AND published='1'
		LIMIT 1
156
(!!!!! 1016.1399841309): SELECT jos_item.*
						FROM jos_item INNER JOIN jos_number ON jos_item.numberID=jos_number.id
						WHERE 1=1
						AND (jos_item.imgMini<>'')
						AND jos_item.type='L'
						AND jos_item.numberID= (
									 SELECT jos_number.id
									 FROM jos_number
									 WHERE jos_number.journalID IN (10)
						
									and jos_number.id in (select distinct jos_number.id from jos_number join jos_item on jos_item.numberid=jos_number.id where jos_item.type='P')
									 ORDER BY (CONVERT(SUBSTRING(issue,1,2),SIGNED) + (CONVERT(SUBSTRING(issue,3,2),SIGNED)*100)) DESC
									 LIMIT 0,1
									 )
						ORDER BY RAND() DESC LIMIT 6
157
(227.21290588379): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294749934 AND published='1'
				union
		SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294749934 AND published='1'
		LIMIT 1
158
(118.01719665527): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294749934 AND published='1'
				union
		SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294749934 AND published='1'
		LIMIT 1
159
(!!!!! 2336.9789123535): SELECT fid FROM jos_deeppockets WHERE cat=10 AND id=294749934 AND type='deeppockets_item' AND published='1' union SELECT fid FROM jos_deeppockets_archive WHERE cat=10 AND id=294749934 AND type='deeppockets_item' AND published='1'  LIMIT 1
160
(64.13459777832): select distinct links.*
from jos_textlinks links
join jos_textlinks_placement placement on links.id=placement.link_id
where journal_id=(10) and (channel_id=215 or channel_id is null)
161
(46.014785766602): select distinct links.*
from jos_textlinks links
join jos_textlinks_placement placement on links.id=placement.link_id
where journal_id=(10) and (channel_id=215 or channel_id is null)
162
(37.908554077148): SELECT livesite FROM jos_dp_categories WHERE id=10 AND published='1' LIMIT 1
163
(157.11784362793): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294749934 AND published='1'
				union
		SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294749934 AND published='1'
		LIMIT 1
164
(612.97416687012): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294749934 AND published='1'
				union
		SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294749934 AND published='1'
		LIMIT 1
165
(50.067901611328): select jos_twitters.link from jos_twitters where cat=10
166
(34.809112548828): select jos_facebook.link from jos_facebook where cat=10
167
(36.001205444336): select jos_google_plus.link from jos_google_plus where cat=10
168
(33.855438232422): select jos_linkedin.link from jos_linkedin where cat=10
169
(360.01205444336): update jos_bannersmanager_banner
			set impmade=impmade+1
			where id in(14615,14202,14203)
170
(!!!!! 11304.140090942): insert into jos_banners_delta values (14615,'2025-04-29 21:11:23','18.119.99.38','view'),(14202,'2025-04-29 21:11:23','18.119.99.38','view'),(14203,'2025-04-29 21:11:23','18.119.99.38','view')