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AI Model Draws Maps to Accurately Identify Tumors and Diseases in Medical Images

By MedImaging International staff writers
Posted on 05 Mar 2024

The interpretation of medical images varies across different regions of the world, particularly in developing countries where doctor shortages and long patient queues are common. Artificial Intelligence (AI) has emerged as a valuable aid in these settings. Automated medical image screening using AI can act as a supportive tool for doctors, pre-scanning images and highlighting unusual findings, such as tumors or early disease indicators (biomarkers), for further medical review. This approach not only saves time but can also enhance the accuracy of diagnoses. However, traditional AI models lack the capability to explain their findings, merely indicating the presence or absence of tumors without further elaboration.

Now, researchers at the Beckman Institute for Advanced Science and Technology (Urbana, IL, USA) have developed an innovative AI model that not only detects anomalies but also explains each decision it makes. This model, unlike standard AI tools, provides interpretive feedback rather than just identifying tumors. Conventionally, AI models assisting doctors are trained with numerous medical images, some showing abnormalities and others normal. These models, upon encountering a new image, assign a probability score indicating the likelihood of a tumor being present.

This novel AI model goes a step further by offering a visual explanation for its decision-making process through what's known as an "equivalency map" (E-map). This E-map transforms the original medical image, such as an X-ray or mammogram, assigning values to different regions based on their medical significance in predicting anomalies. The model aggregates these values to derive a final diagnostic score. This transparent approach allows doctors to see which areas of the map contributed more significantly to the diagnosis and to investigate these regions more closely, enhancing understanding and answering patient inquiries about the diagnostic process.

The research team trained this model on over 20,000 images across three different disease diagnostic tasks. The model was taught to identify early signs of tumors in simulated mammograms, to detect Drusen buildup in retinal images indicative of macular degeneration, and to recognize cardiomegaly in chest X-rays. When compared to traditional AI systems without self-explanation capabilities, this new model demonstrated comparable accuracy: 77.8% in mammograms, 99.1% in retinal OCT images, and 83% in chest X-rays, matching the existing models' accuracy. The success of this model, which employs a deep neural network mimicking the complexity of human neurons, is attributed to its design inspired by simpler, more interpretable linear neural networks. The researchers aim to extend this model's application to various body parts, with the ability to potentially distinguish between different anomalies in future developments.

"The idea is to help catch cancer and disease in its earliest stages — like an X on a map — and understand how the decision was made. Our model will help streamline that process and make it easier on doctors and patients alike,” said Sourya Sengupta, the study’s lead author and a graduate research assistant at the Beckman Institute.

“I am excited about our tool’s direct benefit to society, not only in terms of improving disease diagnoses, but also improving trust and transparency between doctors and patients,” added principal investigator Mark Anastasio, a Beckman Institute researcher and the Donald Biggar Willet Professor and Head of the Illinois Department of Bioengineering.

Related Links:
Beckman Institute 

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96 (513.07678222656): SELECT dp.*, ch.title as channel, exp.name as author_name, exp.specialization as author_specialization, exp.images as author_photo FROM jos_deeppockets as dp LEFT JOIN jos_experts as exp ON exp.id = dp.author LEFT JOIN jos_deeppockets as ch ON dp.fid = ch.id WHERE 1=1 AND dp.id=294800469 AND (dp.type='deeppockets_item' OR dp.type='deeppockets_item_link') AND dp.published='1' LIMIT 1
97 (681.87713623047): SELECT dp.name, dp.id, dp2.name as channel, ex.name as author_name, ex.specialization, ex.images FROM jos_deeppockets as dp LEFT JOIN jos_experts as ex ON ex.id = dp.author LEFT JOIN jos_deeppockets as dp2 ON dp2.id = dp.fid WHERE dp.author != 0 AND dp.cat = 10 AND dp.published = 1 AND ( (dp.fid = 294743300) OR (dp.fid = 294743301) OR (dp.fid = 294743302) OR (dp.fid = 294743303) OR (dp.fid = 294743304) OR (dp.fid = 294743305) OR (dp.fid = 294743306) OR (dp.fid = 294743307) OR (dp.fid = 294743308) OR (dp.fid = 294743309) OR (dp.fid = 294743310) ) ORDER BY RAND() LIMIT 1
98 (458.95576477051): SELECT dp.name, dp.id, dp2.name as channel, ex.name as author_name, ex.specialization, ex.images FROM jos_deeppockets as dp LEFT JOIN jos_experts as ex ON ex.id = dp.author LEFT JOIN jos_deeppockets as dp2 ON dp2.id = dp.fid WHERE dp.author != 0 AND dp.cat = 10 AND dp.published = 1 AND ( (dp.fid = 294743300) OR (dp.fid = 294743301) OR (dp.fid = 294743302) OR (dp.fid = 294743303) OR (dp.fid = 294743304) OR (dp.fid = 294743305) OR (dp.fid = 294743306) OR (dp.fid = 294743307) OR (dp.fid = 294743308) OR (dp.fid = 294743309) OR (dp.fid = 294743310) ) ORDER BY RAND() LIMIT 1
99 (83.92333984375): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294800469 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294800469 AND published='1' LIMIT 1
100 (57.93571472168): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294800469 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294800469 AND published='1' LIMIT 1
101 (102.99682617188): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294800469 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294800469 AND published='1' LIMIT 1
102 (52.928924560547): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294800469 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294800469 AND published='1' LIMIT 1
103 (61.988830566406): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294800469 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294800469 AND published='1' LIMIT 1
104 (48.87580871582): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294800469 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294800469 AND published='1' LIMIT 1
105 (397.92060852051): SELECT * FROM trending_articles WHERE `journal_id` = 10 AND `timestamp` <= NOW() + INTERVAL 7 DAY ORDER BY `order`
106 (!!!!! 106487.03575134): SELECT * FROM jos_deeppockets WHERE jos_deeppockets.cat = 10 AND jos_deeppockets.type = 'deeppockets_item' AND jos_deeppockets.published = 1 AND jos_deeppockets.created + INTERVAL 14 DAY >= NOW() ORDER BY jos_deeppockets.hits DESC LIMIT 7
107 (94.890594482422): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294800469 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294800469 AND published='1' LIMIT 1
108 (46.968460083008): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294800469 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294800469 AND published='1' LIMIT 1
109 (571.01249694824): SELECT fid FROM jos_deeppockets WHERE cat=10 AND id=294800469 AND type='deeppockets_item' AND published='1' union SELECT fid FROM jos_deeppockets_archive WHERE cat=10 AND id=294800469 AND type='deeppockets_item' AND published='1' LIMIT 1
110 (!!!!! 2075592.0410156): ( SELECT dp.id, dp.name, dp.title, dp.video, dp.video_source, dp.created FROM jos_deeppockets AS dp WHERE dp.video != '' AND dp.video_source != '' AND dp.cat = 10 AND dp.published = 1 AND dp.type != 'deeppockets_item_link' ORDER BY created DESC LIMIT 3 ) UNION ( SELECT dpa.id, dpa.name, dpa.title, dpa.video, dpa.video_source, dpa.created FROM jos_deeppockets_archive AS dpa WHERE dpa.video != '' AND dpa.video_source != '' AND dpa.cat = 10 AND dpa.published = 1 AND dpa.type != 'deeppockets_item_link' ORDER BY created DESC LIMIT 3 ) ORDER BY created DESC LIMIT 3
111 (!!!!! 1314018.0110931): ( SELECT dp.id, dp.name, dp.title, dp.video, dp.video_source, dp.created FROM jos_deeppockets AS dp WHERE dp.video != '' AND dp.video_source != '' AND dp.cat = 10 AND dp.published = 1 AND dp.type != 'deeppockets_item_link' ORDER BY created DESC LIMIT 3 ) UNION ( SELECT dpa.id, dpa.name, dpa.title, dpa.video, dpa.video_source, dpa.created FROM jos_deeppockets_archive AS dpa WHERE dpa.video != '' AND dpa.video_source != '' AND dpa.cat = 10 AND dpa.published = 1 AND dpa.type != 'deeppockets_item_link' ORDER BY created DESC LIMIT 3 ) ORDER BY created DESC LIMIT 3
112 (736.95182800293): SELECT dp.id, dp.name, dp.title, dp.video, dp.video_source, dp.created FROM jos_deeppockets AS dp WHERE dp.id = 294800513 LIMIT 1
113 (128.03077697754): SELECT dp.id, dp.name, dp.title, dp.video, dp.video_source, dp.created FROM jos_deeppockets AS dp WHERE dp.id = 294800513 LIMIT 1
114 (349.04479980469): SELECT dp.id, dp.name, dp.title, dp.video, dp.video_source, dp.created FROM jos_deeppockets AS dp WHERE dp.id = 294800359 LIMIT 1
115 (105.85784912109): SELECT dp.id, dp.name, dp.title, dp.video, dp.video_source, dp.created FROM jos_deeppockets AS dp WHERE dp.id = 294800359 LIMIT 1
116 (250.10108947754): SELECT dp.id, dp.name, dp.title, dp.video, dp.video_source, dp.created FROM jos_deeppockets AS dp WHERE dp.id = 294800361 LIMIT 1
117 (46.014785766602): SELECT dp.id, dp.name, dp.title, dp.video, dp.video_source, dp.created FROM jos_deeppockets AS dp WHERE dp.id = 294800361 LIMIT 1
118 (486.13548278809): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294800469 AND (type='deeppockets_item' OR type='deeppockets_item_link') AND published='1' LIMIT 1
119 (216.96090698242): SELECT name FROM jos_deeppockets WHERE id=215
120 (32.901763916016): SELECT name FROM jos_deeppockets WHERE id=215
121 (558.85314941406): SELECT *, DATE_FORMAT(publish_up,'%d %b %Y') AS date_publish_up, DATE_FORMAT(publish_down,'%d %b %Y') AS date_publish_down FROM jos_events WHERE state=1 AND publish_up > NOW() and extra_info REGEXP '((;)|(^))215((;)|($))' AND catid IN (0,110) ORDER BY publish_up ASC LIMIT 3
122 (438.92860412598): SELECT *, DATE_FORMAT(publish_up,'%d %b %Y') AS date_publish_up, DATE_FORMAT(publish_down,'%d %b %Y') AS date_publish_down FROM jos_events WHERE state=1 AND publish_up > NOW() and extra_info REGEXP '((;)|(^))215((;)|($))' AND catid IN (0,110) ORDER BY publish_up ASC LIMIT 3
123 (!!!!! 1049.0417480469): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294800469 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294800469 AND published='1' LIMIT 1
124 (60.081481933594): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294800469 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294800469 AND published='1' LIMIT 1
125 (!!!!! 7950.0675201416): TRUNCATE TABLE jos_trademed_module
126 (941.99180603027): SELECT dp.*, ch.title as channel, exp.name as author_name, exp.specialization as author_specialization, exp.images as author_photo FROM jos_deeppockets as dp LEFT JOIN jos_experts as exp ON exp.id = dp.author LEFT JOIN jos_deeppockets as ch ON dp.fid = ch.id WHERE 1=1 AND dp.cat=10 AND dp.id=294800469 AND (dp.type='deeppockets_item' OR dp.type='deeppockets_item_link') AND dp.published='1' LIMIT 1
127 (530.00450134277): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294800469 AND (type='deeppockets_item' OR type='deeppockets_item_link') AND published='1' LIMIT 1
128 (78.201293945312): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294800469 AND (type='deeppockets_item' OR type='deeppockets_item_link') AND published='1' LIMIT 1
129 (72.956085205078): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294800469 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294800469 AND published='1' LIMIT 1
130 (55.074691772461): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294800469 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294800469 AND published='1' LIMIT 1
131 (!!!!! 1075.0293731689): SELECT jos_item.* FROM jos_item INNER JOIN jos_number ON jos_item.numberID=jos_number.id WHERE 1=1 AND (jos_item.imgMini<>'') AND jos_item.type='L' AND jos_item.numberID= ( SELECT jos_number.id FROM jos_number WHERE jos_number.journalID IN (10) and jos_number.id in (select distinct jos_number.id from jos_number join jos_item on jos_item.numberid=jos_number.id where jos_item.type='P') ORDER BY (CONVERT(SUBSTRING(issue,1,2),SIGNED) + (CONVERT(SUBSTRING(issue,3,2),SIGNED)*100)) DESC LIMIT 0,1 ) ORDER BY RAND() DESC LIMIT 6
132 (69.856643676758): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294800469 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294800469 AND published='1' LIMIT 1
133 (59.843063354492): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294800469 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294800469 AND published='1' LIMIT 1
134 (468.01567077637): SELECT fid FROM jos_deeppockets WHERE cat=10 AND id=294800469 AND type='deeppockets_item' AND published='1' union SELECT fid FROM jos_deeppockets_archive WHERE cat=10 AND id=294800469 AND type='deeppockets_item' AND published='1' LIMIT 1
135 (142.09747314453): select distinct links.* from jos_textlinks links join jos_textlinks_placement placement on links.id=placement.link_id where journal_id=(10) and (channel_id=215 or channel_id is null)
136 (41.007995605469): select distinct links.* from jos_textlinks links join jos_textlinks_placement placement on links.id=placement.link_id where journal_id=(10) and (channel_id=215 or channel_id is null)
137 (33.855438232422): SELECT livesite FROM jos_dp_categories WHERE id=10 AND published='1' LIMIT 1
138 (89.883804321289): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294800469 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294800469 AND published='1' LIMIT 1
139 (44.822692871094): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294800469 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294800469 AND published='1' LIMIT 1
140 (61.03515625): select jos_twitters.link from jos_twitters where cat=10
141 (30.040740966797): select jos_facebook.link from jos_facebook where cat=10
142 (30.040740966797): select jos_google_plus.link from jos_google_plus where cat=10
143 (27.894973754883): select jos_linkedin.link from jos_linkedin where cat=10
144 (260.1146697998): update jos_bannersmanager_banner set impmade=impmade+1 where id in(14615,14202,14203)
145 (!!!!! 1101.016998291): insert into jos_banners_delta values (14615,'2025-04-29 15:59:14','18.191.212.175','view'),(14202,'2025-04-29 15:59:14','18.191.212.175','view'),(14203,'2025-04-29 15:59:14','18.191.212.175','view')