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Non-Invasive Technique Combines Cardiac CT with AI-Powered Blood Flow for Heart Bypass Surgery

By MedImaging International staff writers
Posted on 08 Apr 2024

Researchers have tested a new approach to the guidance, planning, and conducting of heart bypass surgery on patients for the first time, demonstrating that non-invasive cardiac CT, with AI-powered blood flow scanning, is safe and feasible.

In the FAST TRACK CABG study, overseen by a research team at the University of Galway (Galway, Ireland; ), heart surgeons planned and carried out coronary artery bypass grafting (CABG). The procedure was performed based only on non-invasive cardiac-CT scan images using GE Healthcare’s (Chicago, IL, USA) Revolution CT, along with HeartFlow, Inc.’s (Redwood City, CA, USA) AI-powered blood flow analysis of the patient’s coronary arteries. This first-of-its-kind human study demonstrated 99.1% feasibility, indicating that heart bypass surgery performed without utilizing invasive diagnostic catheterization is feasible and safe, based on good diagnostic accuracy provided by the cardiac CT scan and AI-powered blood flow analysis. The study found similar outcomes in terms of safety and effectiveness in patients who had previously undergone bypass surgery guided by conventional invasive angiography, which requires the insertion of a catheter through an artery in the wrist or groin to access diseased arteries and the use of dye to visualize blockages.

Conducted across leading cardiac care hospitals in Europe and the US, the study included 114 patients with severe coronary artery blockages, impacting their heart blood flow. The cardiac CT scans provided in the study delivered exceptional resolution, producing images on par with, or superior to, those obtained through invasive contrast dye injections directly into the heart’s arteries through a catheter. Throughout the trial, detailed cardiovascular imagery and data analyses were performed by the University of Galway team and shared via telemedicine with surgeons at participating hospitals. The HeartFlow Analysis performs an AI-powered blood flow analysis called Fractional Flow Reserve derived from CT (FFRCT) to quantify how poorly the narrowed vessel provides blood to the heart muscle, assisting the surgeon in identifying which of the patient’s vessels require a bypass graft. The FAST TRACK CABG trial's findings indicate that this innovative, less invasive approach to heart bypass surgery is as safe and effective as traditional methods. The study highlights the potential for replacing the risks associated with invasive procedures with non-invasive cardiac CT imaging and AI-based blood flow analysis, offering a significant advancement in cardiac care and surgery planning.

“The results of this trial have the potential to simplify the planning for patients undergoing heart bypass surgery,” said trial chairman Professor Patrick W Serruys, Established Professor of Interventional Medicine and Innovation at University of Galway. “The potential for surgeons to address even the most intricate cases of coronary artery disease using only a non-invasive CT scan, and FFRCT represents a monumental shift in healthcare. Following the example of the surgeon, interventional cardiologists could similarly consider circumventing traditional invasive cineangiography and instead rely solely on CT scans for procedural planning. This approach not only alleviates the diagnostic burden in cath labs but also paves the way for transforming them into dedicated ‘interventional suites’- ultimately enhancing patient workflows.”

Related Links:
University of Galway
GE Healthcare
HeartFlow, Inc.

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64 (67.949295043945): SELECT show_live FROM jos_com_show_setting LIMIT 1

65 (40.054321289062): SELECT show_live FROM jos_com_show_setting LIMIT 1

66 (32.901763916016): SELECT show_live FROM jos_com_show_setting LIMIT 1

67 (31.948089599609): SELECT show_live FROM jos_com_show_setting LIMIT 1

68 (28.133392333984): SELECT show_live FROM jos_com_show_setting LIMIT 1

69 (25.033950805664): SELECT show_live FROM jos_com_show_setting LIMIT 1

70 (25.98762512207): SELECT show_live FROM jos_com_show_setting LIMIT 1

71 (30.040740966797): SELECT show_live FROM jos_com_show_setting LIMIT 1

72 (26.941299438477): SELECT show_live FROM jos_com_show_setting LIMIT 1

73 (25.033950805664): SELECT show_live FROM jos_com_show_setting LIMIT 1

74 (30.994415283203): SELECT show_live FROM jos_com_show_setting LIMIT 1

75 (25.033950805664): SELECT show_live FROM jos_com_show_setting LIMIT 1

76 (25.033950805664): SELECT show_live FROM jos_com_show_setting LIMIT 1

77 (24.795532226562): SELECT show_live FROM jos_com_show_setting LIMIT 1

78 (64.849853515625): SELECT fid FROM jos_deeppockets WHERE cat=10 AND id=294800802 AND (type='deeppockets_item' OR type='deeppockets_item_link') AND published='1' LIMIT 1

79 (35.04753112793): SELECT id,name,title FROM jos_deeppockets WHERE cat=10 AND TYPE='file_folder' AND published=1 AND id != 294743300 AND id != 294743301 AND id != 294743302 AND id != 294743303 AND id != 294743304 AND id != 294743305 AND id != 294743306 AND id != 294743307 AND id != 294743308 AND id != 294743309 AND id != 294743310 AND metakey != 'aacc' ORDER BY `ordering`

80 (52.928924560547): SELECT show_live FROM jos_com_show_setting LIMIT 1

81 (40.054321289062): SELECT show_live FROM jos_com_show_setting LIMIT 1

82 (29.802322387695): SELECT show_live FROM jos_com_show_setting LIMIT 1

83 (28.133392333984): SELECT show_live FROM jos_com_show_setting LIMIT 1

84 (26.941299438477): SELECT show_live FROM jos_com_show_setting LIMIT 1

85 (27.894973754883): SELECT show_live FROM jos_com_show_setting LIMIT 1

86 (25.98762512207): SELECT show_live FROM jos_com_show_setting LIMIT 1

87 (26.941299438477): SELECT show_live FROM jos_com_show_setting LIMIT 1

88 (40.054321289062): SELECT show_live FROM jos_com_show_setting LIMIT 1

89 (28.133392333984): SELECT show_live FROM jos_com_show_setting LIMIT 1

90 (29.087066650391): SELECT show_live FROM jos_com_show_setting LIMIT 1

91 (26.941299438477): SELECT show_live FROM jos_com_show_setting LIMIT 1

92 (26.941299438477): SELECT show_live FROM jos_com_show_setting LIMIT 1

93 (26.941299438477): SELECT show_live FROM jos_com_show_setting LIMIT 1

94 (83.92333984375): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294800802 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294800802 AND published='1' LIMIT 1

95 (48.87580871582): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294800802 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294800802 AND published='1' LIMIT 1

96 (66.041946411133): SELECT dp.*, ch.title as channel, exp.name as author_name, exp.specialization as author_specialization, exp.images as author_photo FROM jos_deeppockets as dp LEFT JOIN jos_experts as exp ON exp.id = dp.author LEFT JOIN jos_deeppockets as ch ON dp.fid = ch.id WHERE 1=1 AND dp.cat=10 AND dp.id=294800802 AND (dp.type='deeppockets_item' OR dp.type='deeppockets_item_link') AND dp.published='1' LIMIT 1

97 (82.015991210938): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294800802 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294800802 AND published='1' LIMIT 1

98 (43.869018554688): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294800802 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294800802 AND published='1' LIMIT 1

99 (432.01446533203): SELECT dp.*, ch.title as channel, exp.name as author_name, exp.specialization as author_specialization, exp.images as author_photo FROM jos_deeppockets as dp LEFT JOIN jos_experts as exp ON exp.id = dp.author LEFT JOIN jos_deeppockets as ch ON dp.fid = ch.id WHERE 1=1 AND dp.id=294800802 AND (dp.type='deeppockets_item' OR dp.type='deeppockets_item_link') AND dp.published='1' LIMIT 1

100 (511.88468933105): SELECT dp.*, ch.title as channel, exp.name as author_name, exp.specialization as author_specialization, exp.images as author_photo FROM jos_deeppockets as dp LEFT JOIN jos_experts as exp ON exp.id = dp.author LEFT JOIN jos_deeppockets as ch ON dp.fid = ch.id WHERE 1=1 AND dp.id=294800796 AND (dp.type='deeppockets_item' OR dp.type='deeppockets_item_link') AND dp.published='1' LIMIT 1

101 (643.01490783691): SELECT dp.name, dp.id, dp2.name as channel, ex.name as author_name, ex.specialization, ex.images FROM jos_deeppockets as dp LEFT JOIN jos_experts as ex ON ex.id = dp.author LEFT JOIN jos_deeppockets as dp2 ON dp2.id = dp.fid WHERE dp.author != 0 AND dp.cat = 10 AND dp.published = 1 AND ( (dp.fid = 294743300) OR (dp.fid = 294743301) OR (dp.fid = 294743302) OR (dp.fid = 294743303) OR (dp.fid = 294743304) OR (dp.fid = 294743305) OR (dp.fid = 294743306) OR (dp.fid = 294743307) OR (dp.fid = 294743308) OR (dp.fid = 294743309) OR (dp.fid = 294743310) ) ORDER BY RAND() LIMIT 1

102 (343.08433532715): SELECT dp.name, dp.id, dp2.name as channel, ex.name as author_name, ex.specialization, ex.images FROM jos_deeppockets as dp LEFT JOIN jos_experts as ex ON ex.id = dp.author LEFT JOIN jos_deeppockets as dp2 ON dp2.id = dp.fid WHERE dp.author != 0 AND dp.cat = 10 AND dp.published = 1 AND ( (dp.fid = 294743300) OR (dp.fid = 294743301) OR (dp.fid = 294743302) OR (dp.fid = 294743303) OR (dp.fid = 294743304) OR (dp.fid = 294743305) OR (dp.fid = 294743306) OR (dp.fid = 294743307) OR (dp.fid = 294743308) OR (dp.fid = 294743309) OR (dp.fid = 294743310) ) ORDER BY RAND() LIMIT 1

103 (83.92333984375): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294800802 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294800802 AND published='1' LIMIT 1

104 (44.822692871094): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294800802 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294800802 AND published='1' LIMIT 1

105 (56.982040405273): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294800802 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294800802 AND published='1' LIMIT 1

106 (36.001205444336): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294800802 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294800802 AND published='1' LIMIT 1

107 (40.054321289062): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294800802 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294800802 AND published='1' LIMIT 1

108 (35.04753112793): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294800802 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294800802 AND published='1' LIMIT 1

109 (54.836273193359): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294800802 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294800802 AND published='1' LIMIT 1

110 (36.001205444336): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294800802 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294800802 AND published='1' LIMIT 1

111 (421.04721069336): SELECT fid FROM jos_deeppockets WHERE cat=10 AND id=294800802 AND type='deeppockets_item' AND published='1' union SELECT fid FROM jos_deeppockets_archive WHERE cat=10 AND id=294800802 AND type='deeppockets_item' AND published='1' LIMIT 1

112 (!!!!! 422126.05476379): ( SELECT dp.id, dp.name, dp.title, dp.video, dp.video_source, dp.created FROM jos_deeppockets AS dp WHERE dp.video != '' AND dp.video_source != '' AND dp.cat = 10 AND dp.published = 1 AND dp.type != 'deeppockets_item_link' ORDER BY created DESC LIMIT 3 ) UNION ( SELECT dpa.id, dpa.name, dpa.title, dpa.video, dpa.video_source, dpa.created FROM jos_deeppockets_archive AS dpa WHERE dpa.video != '' AND dpa.video_source != '' AND dpa.cat = 10 AND dpa.published = 1 AND dpa.type != 'deeppockets_item_link' ORDER BY created DESC LIMIT 3 ) ORDER BY created DESC LIMIT 3

113 (123.02398681641): ( SELECT dp.id, dp.name, dp.title, dp.video, dp.video_source, dp.created FROM jos_deeppockets AS dp WHERE dp.video != '' AND dp.video_source != '' AND dp.cat = 10 AND dp.published = 1 AND dp.type != 'deeppockets_item_link' ORDER BY created DESC LIMIT 3 ) UNION ( SELECT dpa.id, dpa.name, dpa.title, dpa.video, dpa.video_source, dpa.created FROM jos_deeppockets_archive AS dpa WHERE dpa.video != '' AND dpa.video_source != '' AND dpa.cat = 10 AND dpa.published = 1 AND dpa.type != 'deeppockets_item_link' ORDER BY created DESC LIMIT 3 ) ORDER BY created DESC LIMIT 3

114 (406.98051452637): SELECT dp.id, dp.name, dp.title, dp.video, dp.video_source, dp.created FROM jos_deeppockets AS dp WHERE dp.id = 294800513 LIMIT 1

115 (154.97207641602): SELECT dp.id, dp.name, dp.title, dp.video, dp.video_source, dp.created FROM jos_deeppockets AS dp WHERE dp.id = 294800513 LIMIT 1

116 (339.98489379883): SELECT dp.id, dp.name, dp.title, dp.video, dp.video_source, dp.created FROM jos_deeppockets AS dp WHERE dp.id = 294800359 LIMIT 1

117 (45.061111450195): SELECT dp.id, dp.name, dp.title, dp.video, dp.video_source, dp.created FROM jos_deeppockets AS dp WHERE dp.id = 294800359 LIMIT 1

118 (266.07513427734): SELECT dp.id, dp.name, dp.title, dp.video, dp.video_source, dp.created FROM jos_deeppockets AS dp WHERE dp.id = 294800361 LIMIT 1

119 (46.014785766602): SELECT dp.id, dp.name, dp.title, dp.video, dp.video_source, dp.created FROM jos_deeppockets AS dp WHERE dp.id = 294800361 LIMIT 1

120 (298.02322387695): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294800802 AND (type='deeppockets_item' OR type='deeppockets_item_link') AND published='1' LIMIT 1

121 (136.13700866699): SELECT name FROM jos_deeppockets WHERE id=215

122 (126.83868408203): SELECT name FROM jos_deeppockets WHERE id=215

123 (449.18060302734): SELECT *, DATE_FORMAT(publish_up,'%d %b %Y') AS date_publish_up, DATE_FORMAT(publish_down,'%d %b %Y') AS date_publish_down FROM jos_events WHERE state=1 AND publish_up > NOW() and extra_info REGEXP '((;)|(^))215((;)|($))' AND catid IN (0,110) ORDER BY publish_up ASC LIMIT 3

124 (380.9928894043): SELECT *, DATE_FORMAT(publish_up,'%d %b %Y') AS date_publish_up, DATE_FORMAT(publish_down,'%d %b %Y') AS date_publish_down FROM jos_events WHERE state=1 AND publish_up > NOW() and extra_info REGEXP '((;)|(^))215((;)|($))' AND catid IN (0,110) ORDER BY publish_up ASC LIMIT 3

125 (92.029571533203): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294800802 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294800802 AND published='1' LIMIT 1

126 (43.153762817383): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294800802 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294800802 AND published='1' LIMIT 1

127 (374.07875061035): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294800802 AND (type='deeppockets_item' OR type='deeppockets_item_link') AND published='1' LIMIT 1

128 (59.843063354492): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294800802 AND (type='deeppockets_item' OR type='deeppockets_item_link') AND published='1' LIMIT 1

129 (46.014785766602): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294800802 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294800802 AND published='1' LIMIT 1

130 (43.869018554688): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294800802 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294800802 AND published='1' LIMIT 1

131 (!!!!! 1276.0162353516): SELECT jos_item.* FROM jos_item INNER JOIN jos_number ON jos_item.numberID=jos_number.id WHERE 1=1 AND (jos_item.imgMini<>'') AND jos_item.type='L' AND jos_item.numberID= ( SELECT jos_number.id FROM jos_number WHERE jos_number.journalID IN (10) and jos_number.id in (select distinct jos_number.id from jos_number join jos_item on jos_item.numberid=jos_number.id where jos_item.type='P') ORDER BY (CONVERT(SUBSTRING(issue,1,2),SIGNED) + (CONVERT(SUBSTRING(issue,3,2),SIGNED)*100)) DESC LIMIT 0,1 ) ORDER BY RAND() DESC LIMIT 6

132 (46.014785766602): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294800802 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294800802 AND published='1' LIMIT 1

133 (38.14697265625): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294800802 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294800802 AND published='1' LIMIT 1

134 (51.975250244141): SELECT fid FROM jos_deeppockets WHERE cat=10 AND id=294800802 AND type='deeppockets_item' AND published='1' union SELECT fid FROM jos_deeppockets_archive WHERE cat=10 AND id=294800802 AND type='deeppockets_item' AND published='1' LIMIT 1

135 (41.007995605469): select distinct links.* from jos_textlinks links join jos_textlinks_placement placement on links.id=placement.link_id where journal_id=(10) and (channel_id=0 or channel_id is null)

136 (37.193298339844): select distinct links.* from jos_textlinks links join jos_textlinks_placement placement on links.id=placement.link_id where journal_id=(10) and (channel_id=0 or channel_id is null)

137 (56.028366088867): SELECT livesite FROM jos_dp_categories WHERE id=10 AND published='1' LIMIT 1

138 (!!!!! 3182.1727752686): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294800802 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294800802 AND published='1' LIMIT 1

139 (66.995620727539): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294800802 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294800802 AND published='1' LIMIT 1

140 (122.0703125): select jos_twitters.link from jos_twitters where cat=10

141 (39.100646972656): select jos_facebook.link from jos_facebook where cat=10

142 (34.093856811523): select jos_google_plus.link from jos_google_plus where cat=10

143 (29.087066650391): select jos_linkedin.link from jos_linkedin where cat=10

144 (260.1146697998): update jos_bannersmanager_banner set impmade=impmade+1 where id in(14615,14202,14203)

145 (!!!!! 1283.1687927246): insert into jos_banners_delta values (14615,'2025-04-29 15:35:04','3.144.12.160','view'),(14202,'2025-04-29 15:35:04','3.144.12.160','view'),(14203,'2025-04-29 15:35:04','3.144.12.160','view')

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