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AI-Driven Chest X-Ray Solution Offers Enhanced Lung Nodule Detection

By MedImaging International staff writers
Posted on 16 Jan 2024

Chest X-rays (CXRs) are a fundamental diagnostic tool, accounting for about 25% of all diagnostic imaging procedures annually. Their widespread use in diagnosing various cardiothoracic conditions is due to their accessibility, mobility, cost-effectiveness, and familiarity compared to other imaging modalities. However, CXRs are prone to misinterpretation, with error rates up to 30%. Previous studies have highlighted this issue, showing inter-radiologist and physician agreement rates as low as 78%. Misinterpretations can have serious implications, as revealed by studies where 19% of lung tumors, appearing as pulmonary nodules on CXRs, were initially missed, potentially leading to fatal outcomes for patients. Now, a novel CXR-based solution uses artificial intelligence (AI) to identify and localize potentially malignant pulmonary nodules, thereby significantly aiding the fight against lung cancer.

qXR for Lung Nodule (qXR – LN) from Qure.ai (Mumbai, India) represents a breakthrough in computer-aided detection software. It is designed to identify and highlight suspected pulmonary nodules ranging from 6 to 30 mm, specifically targeting the incidental adult population. This tool, a game-changer in diagnostic technology, can also function as a crucial second reader in reviewing adult frontal (AP/PA) chest radiographs taken on digital radiographic systems. Qure.ai has validated the safety and efficacy of its lung nodule device through two pivotal studies. The first study confirmed its standalone effectiveness, achieving a 94% Area Under the Curve (AUC) for nodule detection. The second study demonstrated that, with qXR-LN assistance, some emergency room physicians and pulmonologists nearly matched or even exceeded the baseline performance of radiologists.

The early detection of lung nodules in plain film radiography is crucial for the timely identification of cancer risks, allowing for prompt intervention and improved patient outcomes. Accurate nodule detection is essential for treatment planning, disease progression monitoring, and reducing false positives and negatives, thereby enhancing healthcare efficiency. Innovations like qXR-LN are pivotal in evolving pulmonary imaging, especially in the field of oncology. The criticality of early-stage lung cancer detection underscores the importance of tools like qXR-LN in identifying incidental nodules at an early stage. With its recent FDA clearance, qXR-LN stands as the only FDA-cleared solution for detecting and localizing lung nodules using computer vision, targeting radiologists, pulmonologists, and emergency room physicians as its primary users.

“With this latest addition to our large series of recent FDA clearances, we are steadfast in our unwavering commitment to the US healthcare space,” said Prashant Warier, Co-Founder and CEO of Qure.ai. “Having already effectively deployed and implemented this solution globally, this clearance marks yet another ground-breaking leap in our pioneering efforts to combat lung cancer. Our heightened emphasis on the North American marketplace solidifies our commitment to making a meaningful impact in the fight against this deadly disease and underscores our dedication to advancing healthcare through innovation, providing a transformative solution enhancing the early detection of cancer and ultimately improving patient outcomes.”

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84 (28.133392333984): SELECT show_live FROM jos_com_show_setting LIMIT 1

85 (28.848648071289): SELECT show_live FROM jos_com_show_setting LIMIT 1

86 (92.983245849609): SELECT show_live FROM jos_com_show_setting LIMIT 1

87 (61.03515625): SELECT show_live FROM jos_com_show_setting LIMIT 1

88 (44.107437133789): SELECT show_live FROM jos_com_show_setting LIMIT 1

89 (28.848648071289): SELECT show_live FROM jos_com_show_setting LIMIT 1

90 (27.894973754883): SELECT show_live FROM jos_com_show_setting LIMIT 1

91 (26.941299438477): SELECT show_live FROM jos_com_show_setting LIMIT 1

92 (26.941299438477): SELECT show_live FROM jos_com_show_setting LIMIT 1

93 (26.941299438477): SELECT show_live FROM jos_com_show_setting LIMIT 1

94 (75.101852416992): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294799929 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294799929 AND published='1' LIMIT 1

95 (44.107437133789): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294799929 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294799929 AND published='1' LIMIT 1

96 (62.942504882812): SELECT dp.*, ch.title as channel, exp.name as author_name, exp.specialization as author_specialization, exp.images as author_photo FROM jos_deeppockets as dp LEFT JOIN jos_experts as exp ON exp.id = dp.author LEFT JOIN jos_deeppockets as ch ON dp.fid = ch.id WHERE 1=1 AND dp.cat=10 AND dp.id=294799929 AND (dp.type='deeppockets_item' OR dp.type='deeppockets_item_link') AND dp.published='1' LIMIT 1

97 (72.956085205078): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294799929 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294799929 AND published='1' LIMIT 1

98 (53.167343139648): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294799929 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294799929 AND published='1' LIMIT 1

99 (340.22331237793): SELECT dp.*, ch.title as channel, exp.name as author_name, exp.specialization as author_specialization, exp.images as author_photo FROM jos_deeppockets as dp LEFT JOIN jos_experts as exp ON exp.id = dp.author LEFT JOIN jos_deeppockets as ch ON dp.fid = ch.id WHERE 1=1 AND dp.id=294799929 AND (dp.type='deeppockets_item' OR dp.type='deeppockets_item_link') AND dp.published='1' LIMIT 1

100 (550.0316619873): SELECT dp.name, dp.id, dp2.name as channel, ex.name as author_name, ex.specialization, ex.images FROM jos_deeppockets as dp LEFT JOIN jos_experts as ex ON ex.id = dp.author LEFT JOIN jos_deeppockets as dp2 ON dp2.id = dp.fid WHERE dp.author != 0 AND dp.cat = 10 AND dp.published = 1 AND ( (dp.fid = 294743300) OR (dp.fid = 294743301) OR (dp.fid = 294743302) OR (dp.fid = 294743303) OR (dp.fid = 294743304) OR (dp.fid = 294743305) OR (dp.fid = 294743306) OR (dp.fid = 294743307) OR (dp.fid = 294743308) OR (dp.fid = 294743309) OR (dp.fid = 294743310) ) ORDER BY RAND() LIMIT 1

101 (308.99047851562): SELECT dp.name, dp.id, dp2.name as channel, ex.name as author_name, ex.specialization, ex.images FROM jos_deeppockets as dp LEFT JOIN jos_experts as ex ON ex.id = dp.author LEFT JOIN jos_deeppockets as dp2 ON dp2.id = dp.fid WHERE dp.author != 0 AND dp.cat = 10 AND dp.published = 1 AND ( (dp.fid = 294743300) OR (dp.fid = 294743301) OR (dp.fid = 294743302) OR (dp.fid = 294743303) OR (dp.fid = 294743304) OR (dp.fid = 294743305) OR (dp.fid = 294743306) OR (dp.fid = 294743307) OR (dp.fid = 294743308) OR (dp.fid = 294743309) OR (dp.fid = 294743310) ) ORDER BY RAND() LIMIT 1

102 (90.837478637695): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294799929 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294799929 AND published='1' LIMIT 1

103 (57.93571472168): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294799929 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294799929 AND published='1' LIMIT 1

104 (62.942504882812): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294799929 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294799929 AND published='1' LIMIT 1

105 (37.193298339844): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294799929 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294799929 AND published='1' LIMIT 1

106 (189.06593322754): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294799929 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294799929 AND published='1' LIMIT 1

107 (51.975250244141): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294799929 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294799929 AND published='1' LIMIT 1

108 (267.02880859375): SELECT * FROM trending_articles WHERE `journal_id` = 10 AND `timestamp` <= NOW() + INTERVAL 7 DAY ORDER BY `order`

109 (!!!!! 26314.02015686): SELECT * FROM jos_deeppockets WHERE jos_deeppockets.cat = 10 AND jos_deeppockets.type = 'deeppockets_item' AND jos_deeppockets.published = 1 AND jos_deeppockets.created + INTERVAL 14 DAY >= NOW() ORDER BY jos_deeppockets.hits DESC LIMIT 7

110 (102.99682617188): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294799929 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294799929 AND published='1' LIMIT 1

111 (59.843063354492): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294799929 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294799929 AND published='1' LIMIT 1

112 (435.82916259766): SELECT fid FROM jos_deeppockets WHERE cat=10 AND id=294799929 AND type='deeppockets_item' AND published='1' union SELECT fid FROM jos_deeppockets_archive WHERE cat=10 AND id=294799929 AND type='deeppockets_item' AND published='1' LIMIT 1

113 (!!!!! 411406.04019165): ( SELECT dp.id, dp.name, dp.title, dp.video, dp.video_source, dp.created FROM jos_deeppockets AS dp WHERE dp.video != '' AND dp.video_source != '' AND dp.cat = 10 AND dp.published = 1 AND dp.type != 'deeppockets_item_link' ORDER BY created DESC LIMIT 3 ) UNION ( SELECT dpa.id, dpa.name, dpa.title, dpa.video, dpa.video_source, dpa.created FROM jos_deeppockets_archive AS dpa WHERE dpa.video != '' AND dpa.video_source != '' AND dpa.cat = 10 AND dpa.published = 1 AND dpa.type != 'deeppockets_item_link' ORDER BY created DESC LIMIT 3 ) ORDER BY created DESC LIMIT 3

114 (75.817108154297): ( SELECT dp.id, dp.name, dp.title, dp.video, dp.video_source, dp.created FROM jos_deeppockets AS dp WHERE dp.video != '' AND dp.video_source != '' AND dp.cat = 10 AND dp.published = 1 AND dp.type != 'deeppockets_item_link' ORDER BY created DESC LIMIT 3 ) UNION ( SELECT dpa.id, dpa.name, dpa.title, dpa.video, dpa.video_source, dpa.created FROM jos_deeppockets_archive AS dpa WHERE dpa.video != '' AND dpa.video_source != '' AND dpa.cat = 10 AND dpa.published = 1 AND dpa.type != 'deeppockets_item_link' ORDER BY created DESC LIMIT 3 ) ORDER BY created DESC LIMIT 3

115 (215.05355834961): SELECT dp.id, dp.name, dp.title, dp.video, dp.video_source, dp.created FROM jos_deeppockets AS dp WHERE dp.id = 294800513 LIMIT 1

116 (53.167343139648): SELECT dp.id, dp.name, dp.title, dp.video, dp.video_source, dp.created FROM jos_deeppockets AS dp WHERE dp.id = 294800513 LIMIT 1

117 (143.05114746094): SELECT dp.id, dp.name, dp.title, dp.video, dp.video_source, dp.created FROM jos_deeppockets AS dp WHERE dp.id = 294800359 LIMIT 1

118 (39.100646972656): SELECT dp.id, dp.name, dp.title, dp.video, dp.video_source, dp.created FROM jos_deeppockets AS dp WHERE dp.id = 294800359 LIMIT 1

119 (169.03877258301): SELECT dp.id, dp.name, dp.title, dp.video, dp.video_source, dp.created FROM jos_deeppockets AS dp WHERE dp.id = 294800361 LIMIT 1

120 (44.107437133789): SELECT dp.id, dp.name, dp.title, dp.video, dp.video_source, dp.created FROM jos_deeppockets AS dp WHERE dp.id = 294800361 LIMIT 1

121 (263.92936706543): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294799929 AND (type='deeppockets_item' OR type='deeppockets_item_link') AND published='1' LIMIT 1

122 (108.95729064941): SELECT name FROM jos_deeppockets WHERE id=211

123 (35.04753112793): SELECT name FROM jos_deeppockets WHERE id=211

124 (442.9817199707): SELECT *, DATE_FORMAT(publish_up,'%d %b %Y') AS date_publish_up, DATE_FORMAT(publish_down,'%d %b %Y') AS date_publish_down FROM jos_events WHERE state=1 AND publish_up > NOW() and extra_info REGEXP '((;)|(^))211((;)|($))' AND catid IN (0,110) ORDER BY publish_up ASC LIMIT 3

125 (382.1849822998): SELECT *, DATE_FORMAT(publish_up,'%d %b %Y') AS date_publish_up, DATE_FORMAT(publish_down,'%d %b %Y') AS date_publish_down FROM jos_events WHERE state=1 AND publish_up > NOW() and extra_info REGEXP '((;)|(^))211((;)|($))' AND catid IN (0,110) ORDER BY publish_up ASC LIMIT 3

126 (76.055526733398): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294799929 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294799929 AND published='1' LIMIT 1

127 (54.121017456055): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294799929 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294799929 AND published='1' LIMIT 1

128 (!!!!! 7948.1601715088): TRUNCATE TABLE jos_trademed_module

129 (103.95050048828): SELECT dp.*, ch.title as channel, exp.name as author_name, exp.specialization as author_specialization, exp.images as author_photo FROM jos_deeppockets as dp LEFT JOIN jos_experts as exp ON exp.id = dp.author LEFT JOIN jos_deeppockets as ch ON dp.fid = ch.id WHERE 1=1 AND dp.cat=10 AND dp.id=294799929 AND (dp.type='deeppockets_item' OR dp.type='deeppockets_item_link') AND dp.published='1' LIMIT 1

130 (716.9246673584): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294799929 AND (type='deeppockets_item' OR type='deeppockets_item_link') AND published='1' LIMIT 1

131 (60.081481933594): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294799929 AND (type='deeppockets_item' OR type='deeppockets_item_link') AND published='1' LIMIT 1

132 (58.889389038086): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294799929 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294799929 AND published='1' LIMIT 1

133 (39.100646972656): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294799929 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294799929 AND published='1' LIMIT 1

134 (!!!!! 1204.9674987793): SELECT jos_item.* FROM jos_item INNER JOIN jos_number ON jos_item.numberID=jos_number.id WHERE 1=1 AND (jos_item.imgMini<>'') AND jos_item.type='L' AND jos_item.numberID= ( SELECT jos_number.id FROM jos_number WHERE jos_number.journalID IN (10) and jos_number.id in (select distinct jos_number.id from jos_number join jos_item on jos_item.numberid=jos_number.id where jos_item.type='P') ORDER BY (CONVERT(SUBSTRING(issue,1,2),SIGNED) + (CONVERT(SUBSTRING(issue,3,2),SIGNED)*100)) DESC LIMIT 0,1 ) ORDER BY RAND() DESC LIMIT 6

135 (54.121017456055): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294799929 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294799929 AND published='1' LIMIT 1

136 (41.961669921875): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294799929 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294799929 AND published='1' LIMIT 1

137 (32.901763916016): SELECT fid FROM jos_deeppockets WHERE cat=10 AND id=294799929 AND type='deeppockets_item' AND published='1' union SELECT fid FROM jos_deeppockets_archive WHERE cat=10 AND id=294799929 AND type='deeppockets_item' AND published='1' LIMIT 1

138 (29.087066650391): select distinct links.* from jos_textlinks links join jos_textlinks_placement placement on links.id=placement.link_id where journal_id=(10) and (channel_id=211 or channel_id is null)

139 (27.179718017578): select distinct links.* from jos_textlinks links join jos_textlinks_placement placement on links.id=placement.link_id where journal_id=(10) and (channel_id=211 or channel_id is null)

140 (149.01161193848): SELECT livesite FROM jos_dp_categories WHERE id=10 AND published='1' LIMIT 1

141 (65.088272094727): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294799929 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294799929 AND published='1' LIMIT 1

142 (38.862228393555): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294799929 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294799929 AND published='1' LIMIT 1

143 (118.01719665527): select jos_twitters.link from jos_twitters where cat=10

144 (41.007995605469): select jos_facebook.link from jos_facebook where cat=10

145 (28.133392333984): select jos_google_plus.link from jos_google_plus where cat=10

146 (26.941299438477): select jos_linkedin.link from jos_linkedin where cat=10

147 (266.07513427734): update jos_bannersmanager_banner set impmade=impmade+1 where id in(14615,14202,14203)

148 (!!!!! 1255.0354003906): insert into jos_banners_delta values (14615,'2025-04-29 15:37:48','18.216.82.12','view'),(14202,'2025-04-29 15:37:48','18.216.82.12','view'),(14203,'2025-04-29 15:37:48','18.216.82.12','view')

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