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Artificial Intelligence Software Cuts Prostate MRI Read Times by 56%

By MedImaging International staff writers
Posted on 08 May 2023

Multiparametric MRI (mpMRI) serves as a noninvasive triage tool that can not only detect clinically significant prostate cancer (csPCa) lesions but also provide information on locoregional staging and biopsy. When combined with serum prostate-specific antigen (PSA) tests, an "MRI diagnosis pathway" may help reduce excessive biopsies and overtreatment of indolent lesions. CAD systems can improve radiologists' diagnostic performance and minimize interpretation inconsistencies. While many studies suggest that AI-based CAD systems have potential clinical utility in csPCa detection, their generalization and performance on outside datasets have not been thoroughly explored.

Now, a study by researchers at Peking University First Hospital (Beijing, China) has found that AI software can decrease false positive reports of csPCa while also reducing radiologist read times. Using proprietary deep learning-based AI software, radiologists were able to halve their read times when interpreting mpMRI scans of patients with suspected prostate cancer, dropping from 423 to 185 seconds per exam. Additionally, the AI software improved sensitivity and specificity. The study's significance lies in the testing method, as it involved 11 different MRI systems from three institutions, demonstrating the software's reproducibility and real-world utility, which has been lacking in previous CAD system studies.

In the study, 480 mpMRI images with 349 csPCa lesions in 180 cases were used. Sixteen radiologists with varying experience levels from four hospitals participated, interpreting scans with and without the software before reinterpreting the same scans four weeks later in switched mode. The software increased sensitivity from 40.1% to 59.0% and specificity from 57.7% to 71.7%. It also reduced reading times by 56.3% and improved diagnostic confidence scores from 3.9 to 4.3. Despite the study's limitations, the researchers believe their results indicate how the AI software could benefit patients and providers in real-world clinical situations.

“The strength of our study is that the external data were collected from three different medical institutions,” the team noted. “The mpMRI images were acquired using a total of 11 different MR devices with some variation in scan parameters. Thus, the data are very heterogeneous, which is a challenging task for AI algorithms.”

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70 (41.961669921875): SELECT id,name,title FROM jos_deeppockets WHERE cat=10 AND TYPE='file_folder' AND published=1 AND id != 294743300 AND id != 294743301 AND id != 294743302 AND id != 294743303 AND id != 294743304 AND id != 294743305 AND id != 294743306 AND id != 294743307 AND id != 294743308 AND id != 294743309 AND id != 294743310 AND metakey != 'aacc' ORDER BY `ordering`

71 (47.206878662109): SELECT show_live FROM jos_com_show_setting LIMIT 1

72 (30.040740966797): SELECT show_live FROM jos_com_show_setting LIMIT 1

73 (26.941299438477): SELECT show_live FROM jos_com_show_setting LIMIT 1

74 (27.894973754883): SELECT show_live FROM jos_com_show_setting LIMIT 1

75 (26.941299438477): SELECT show_live FROM jos_com_show_setting LIMIT 1

76 (26.941299438477): SELECT show_live FROM jos_com_show_setting LIMIT 1

77 (61.988830566406): SELECT show_live FROM jos_com_show_setting LIMIT 1

78 (28.848648071289): SELECT show_live FROM jos_com_show_setting LIMIT 1

79 (27.894973754883): SELECT show_live FROM jos_com_show_setting LIMIT 1

80 (26.941299438477): SELECT show_live FROM jos_com_show_setting LIMIT 1

81 (25.98762512207): SELECT show_live FROM jos_com_show_setting LIMIT 1

82 (28.133392333984): SELECT show_live FROM jos_com_show_setting LIMIT 1

83 (25.98762512207): SELECT show_live FROM jos_com_show_setting LIMIT 1

84 (27.179718017578): SELECT show_live FROM jos_com_show_setting LIMIT 1

85 (41.961669921875): SELECT fid FROM jos_deeppockets WHERE cat=10 AND id=294797105 AND (type='deeppockets_item' OR type='deeppockets_item_link') AND published='1' LIMIT 1

86 (34.093856811523): SELECT id,name,title FROM jos_deeppockets WHERE cat=10 AND TYPE='file_folder' AND published=1 AND id != 294743300 AND id != 294743301 AND id != 294743302 AND id != 294743303 AND id != 294743304 AND id != 294743305 AND id != 294743306 AND id != 294743307 AND id != 294743308 AND id != 294743309 AND id != 294743310 AND metakey != 'aacc' ORDER BY `ordering`

87 (47.206878662109): SELECT show_live FROM jos_com_show_setting LIMIT 1

88 (29.802322387695): SELECT show_live FROM jos_com_show_setting LIMIT 1

89 (27.894973754883): SELECT show_live FROM jos_com_show_setting LIMIT 1

90 (28.133392333984): SELECT show_live FROM jos_com_show_setting LIMIT 1

91 (27.179718017578): SELECT show_live FROM jos_com_show_setting LIMIT 1

92 (26.941299438477): SELECT show_live FROM jos_com_show_setting LIMIT 1

93 (38.862228393555): SELECT show_live FROM jos_com_show_setting LIMIT 1

94 (28.133392333984): SELECT show_live FROM jos_com_show_setting LIMIT 1

95 (26.941299438477): SELECT show_live FROM jos_com_show_setting LIMIT 1

96 (27.894973754883): SELECT show_live FROM jos_com_show_setting LIMIT 1

97 (26.941299438477): SELECT show_live FROM jos_com_show_setting LIMIT 1

98 (26.941299438477): SELECT show_live FROM jos_com_show_setting LIMIT 1

99 (26.941299438477): SELECT show_live FROM jos_com_show_setting LIMIT 1

100 (27.894973754883): SELECT show_live FROM jos_com_show_setting LIMIT 1

101 (77.009201049805): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294797105 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294797105 AND published='1' LIMIT 1

102 (42.915344238281): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294797105 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294797105 AND published='1' LIMIT 1

103 (76.055526733398): SELECT dp.*, ch.title as channel, exp.name as author_name, exp.specialization as author_specialization, exp.images as author_photo FROM jos_deeppockets as dp LEFT JOIN jos_experts as exp ON exp.id = dp.author LEFT JOIN jos_deeppockets as ch ON dp.fid = ch.id WHERE 1=1 AND dp.cat=10 AND dp.id=294797105 AND (dp.type='deeppockets_item' OR dp.type='deeppockets_item_link') AND dp.published='1' LIMIT 1

104 (61.988830566406): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294797105 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294797105 AND published='1' LIMIT 1

105 (38.862228393555): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294797105 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294797105 AND published='1' LIMIT 1

106 (399.11270141602): SELECT dp.*, ch.title as channel, exp.name as author_name, exp.specialization as author_specialization, exp.images as author_photo FROM jos_deeppockets as dp LEFT JOIN jos_experts as exp ON exp.id = dp.author LEFT JOIN jos_deeppockets as ch ON dp.fid = ch.id WHERE 1=1 AND dp.id=294797105 AND (dp.type='deeppockets_item' OR dp.type='deeppockets_item_link') AND dp.published='1' LIMIT 1

107 (80.82389831543): SELECT dp.*, ch.title as channel, exp.name as author_name, exp.specialization as author_specialization, exp.images as author_photo FROM jos_deeppockets as dp LEFT JOIN jos_experts as exp ON exp.id = dp.author LEFT JOIN jos_deeppockets as ch ON dp.fid = ch.id WHERE 1=1 AND dp.id=294797098 AND (dp.type='deeppockets_item' OR dp.type='deeppockets_item_link') AND dp.published='1' LIMIT 1

108 (379.08554077148): SELECT dp.*, ch.title as channel, exp.name as author_name, exp.specialization as author_specialization, exp.images as author_photo FROM jos_deeppockets_archive as dp LEFT JOIN jos_experts as exp ON exp.id = dp.author LEFT JOIN jos_deeppockets as ch ON dp.fid = ch.id WHERE 1=1 AND dp.id=294797098 AND (dp.type='deeppockets_item' OR dp.type='deeppockets_item_link') AND dp.published='1' LIMIT 1

109 (598.19221496582): SELECT dp.name, dp.id, dp2.name as channel, ex.name as author_name, ex.specialization, ex.images FROM jos_deeppockets as dp LEFT JOIN jos_experts as ex ON ex.id = dp.author LEFT JOIN jos_deeppockets as dp2 ON dp2.id = dp.fid WHERE dp.author != 0 AND dp.cat = 10 AND dp.published = 1 AND ( (dp.fid = 294743300) OR (dp.fid = 294743301) OR (dp.fid = 294743302) OR (dp.fid = 294743303) OR (dp.fid = 294743304) OR (dp.fid = 294743305) OR (dp.fid = 294743306) OR (dp.fid = 294743307) OR (dp.fid = 294743308) OR (dp.fid = 294743309) OR (dp.fid = 294743310) ) ORDER BY RAND() LIMIT 1

110 (359.05838012695): SELECT dp.name, dp.id, dp2.name as channel, ex.name as author_name, ex.specialization, ex.images FROM jos_deeppockets as dp LEFT JOIN jos_experts as ex ON ex.id = dp.author LEFT JOIN jos_deeppockets as dp2 ON dp2.id = dp.fid WHERE dp.author != 0 AND dp.cat = 10 AND dp.published = 1 AND ( (dp.fid = 294743300) OR (dp.fid = 294743301) OR (dp.fid = 294743302) OR (dp.fid = 294743303) OR (dp.fid = 294743304) OR (dp.fid = 294743305) OR (dp.fid = 294743306) OR (dp.fid = 294743307) OR (dp.fid = 294743308) OR (dp.fid = 294743309) OR (dp.fid = 294743310) ) ORDER BY RAND() LIMIT 1

111 (61.988830566406): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294797105 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294797105 AND published='1' LIMIT 1

112 (43.869018554688): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294797105 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294797105 AND published='1' LIMIT 1

113 (85.115432739258): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294797105 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294797105 AND published='1' LIMIT 1

114 (40.054321289062): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294797105 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294797105 AND published='1' LIMIT 1

115 (59.127807617188): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294797105 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294797105 AND published='1' LIMIT 1

116 (45.061111450195): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294797105 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294797105 AND published='1' LIMIT 1

117 (312.08992004395): SELECT * FROM trending_articles WHERE `journal_id` = 10 AND `timestamp` <= NOW() + INTERVAL 7 DAY ORDER BY `order`

118 (!!!!! 22022.008895874): SELECT * FROM jos_deeppockets WHERE jos_deeppockets.cat = 10 AND jos_deeppockets.type = 'deeppockets_item' AND jos_deeppockets.published = 1 AND jos_deeppockets.created + INTERVAL 14 DAY >= NOW() ORDER BY jos_deeppockets.hits DESC LIMIT 7

119 (123.02398681641): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294797105 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294797105 AND published='1' LIMIT 1

120 (47.922134399414): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294797105 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294797105 AND published='1' LIMIT 1

121 (375.98609924316): SELECT fid FROM jos_deeppockets WHERE cat=10 AND id=294797105 AND type='deeppockets_item' AND published='1' union SELECT fid FROM jos_deeppockets_archive WHERE cat=10 AND id=294797105 AND type='deeppockets_item' AND published='1' LIMIT 1

122 (!!!!! 415940.04631042): ( SELECT dp.id, dp.name, dp.title, dp.video, dp.video_source, dp.created FROM jos_deeppockets AS dp WHERE dp.video != '' AND dp.video_source != '' AND dp.cat = 10 AND dp.published = 1 AND dp.type != 'deeppockets_item_link' ORDER BY created DESC LIMIT 3 ) UNION ( SELECT dpa.id, dpa.name, dpa.title, dpa.video, dpa.video_source, dpa.created FROM jos_deeppockets_archive AS dpa WHERE dpa.video != '' AND dpa.video_source != '' AND dpa.cat = 10 AND dpa.published = 1 AND dpa.type != 'deeppockets_item_link' ORDER BY created DESC LIMIT 3 ) ORDER BY created DESC LIMIT 3

123 (113.01040649414): ( SELECT dp.id, dp.name, dp.title, dp.video, dp.video_source, dp.created FROM jos_deeppockets AS dp WHERE dp.video != '' AND dp.video_source != '' AND dp.cat = 10 AND dp.published = 1 AND dp.type != 'deeppockets_item_link' ORDER BY created DESC LIMIT 3 ) UNION ( SELECT dpa.id, dpa.name, dpa.title, dpa.video, dpa.video_source, dpa.created FROM jos_deeppockets_archive AS dpa WHERE dpa.video != '' AND dpa.video_source != '' AND dpa.cat = 10 AND dpa.published = 1 AND dpa.type != 'deeppockets_item_link' ORDER BY created DESC LIMIT 3 ) ORDER BY created DESC LIMIT 3

124 (56.028366088867): SELECT dp.id, dp.name, dp.title, dp.video, dp.video_source, dp.created FROM jos_deeppockets AS dp WHERE dp.id = 294800513 LIMIT 1

125 (35.04753112793): SELECT dp.id, dp.name, dp.title, dp.video, dp.video_source, dp.created FROM jos_deeppockets AS dp WHERE dp.id = 294800513 LIMIT 1

126 (51.975250244141): SELECT dp.id, dp.name, dp.title, dp.video, dp.video_source, dp.created FROM jos_deeppockets AS dp WHERE dp.id = 294800359 LIMIT 1

127 (32.901763916016): SELECT dp.id, dp.name, dp.title, dp.video, dp.video_source, dp.created FROM jos_deeppockets AS dp WHERE dp.id = 294800359 LIMIT 1

128 (51.021575927734): SELECT dp.id, dp.name, dp.title, dp.video, dp.video_source, dp.created FROM jos_deeppockets AS dp WHERE dp.id = 294800361 LIMIT 1

129 (47.922134399414): SELECT dp.id, dp.name, dp.title, dp.video, dp.video_source, dp.created FROM jos_deeppockets AS dp WHERE dp.id = 294800361 LIMIT 1

130 (565.0520324707): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294797105 AND (type='deeppockets_item' OR type='deeppockets_item_link') AND published='1' LIMIT 1

131 (332.11708068848): SELECT name FROM jos_deeppockets WHERE id=216

132 (51.975250244141): SELECT name FROM jos_deeppockets WHERE id=216

133 (602.00691223145): SELECT *, DATE_FORMAT(publish_up,'%d %b %Y') AS date_publish_up, DATE_FORMAT(publish_down,'%d %b %Y') AS date_publish_down FROM jos_events WHERE state=1 AND publish_up > NOW() and extra_info REGEXP '((;)|(^))216((;)|($))' AND catid IN (0,110) ORDER BY publish_up ASC LIMIT 3

134 (555.03845214844): SELECT *, DATE_FORMAT(publish_up,'%d %b %Y') AS date_publish_up, DATE_FORMAT(publish_down,'%d %b %Y') AS date_publish_down FROM jos_events WHERE state=1 AND publish_up > NOW() and extra_info REGEXP '((;)|(^))216((;)|($))' AND catid IN (0,110) ORDER BY publish_up ASC LIMIT 3

135 (80.82389831543): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294797105 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294797105 AND published='1' LIMIT 1

136 (79.870223999023): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294797105 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294797105 AND published='1' LIMIT 1

137 (!!!!! 10391.9506073): TRUNCATE TABLE jos_trademed_module

138 (100.85105895996): SELECT dp.*, ch.title as channel, exp.name as author_name, exp.specialization as author_specialization, exp.images as author_photo FROM jos_deeppockets as dp LEFT JOIN jos_experts as exp ON exp.id = dp.author LEFT JOIN jos_deeppockets as ch ON dp.fid = ch.id WHERE 1=1 AND dp.cat=10 AND dp.id=294797105 AND (dp.type='deeppockets_item' OR dp.type='deeppockets_item_link') AND dp.published='1' LIMIT 1

139 (689.02969360352): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294797105 AND (type='deeppockets_item' OR type='deeppockets_item_link') AND published='1' LIMIT 1

140 (90.122222900391): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294797105 AND (type='deeppockets_item' OR type='deeppockets_item_link') AND published='1' LIMIT 1

141 (89.883804321289): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294797105 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294797105 AND published='1' LIMIT 1

142 (49.829483032227): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294797105 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294797105 AND published='1' LIMIT 1

143 (!!!!! 1425.02784729): SELECT jos_item.* FROM jos_item INNER JOIN jos_number ON jos_item.numberID=jos_number.id WHERE 1=1 AND (jos_item.imgMini<>'') AND jos_item.type='L' AND jos_item.numberID= ( SELECT jos_number.id FROM jos_number WHERE jos_number.journalID IN (10) and jos_number.id in (select distinct jos_number.id from jos_number join jos_item on jos_item.numberid=jos_number.id where jos_item.type='P') ORDER BY (CONVERT(SUBSTRING(issue,1,2),SIGNED) + (CONVERT(SUBSTRING(issue,3,2),SIGNED)*100)) DESC LIMIT 0,1 ) ORDER BY RAND() DESC LIMIT 6

144 (78.916549682617): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294797105 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294797105 AND published='1' LIMIT 1

145 (53.882598876953): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294797105 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294797105 AND published='1' LIMIT 1

146 (72.002410888672): SELECT fid FROM jos_deeppockets WHERE cat=10 AND id=294797105 AND type='deeppockets_item' AND published='1' union SELECT fid FROM jos_deeppockets_archive WHERE cat=10 AND id=294797105 AND type='deeppockets_item' AND published='1' LIMIT 1

147 (63.896179199219): select distinct links.* from jos_textlinks links join jos_textlinks_placement placement on links.id=placement.link_id where journal_id=(10) and (channel_id=0 or channel_id is null)

148 (63.896179199219): select distinct links.* from jos_textlinks links join jos_textlinks_placement placement on links.id=placement.link_id where journal_id=(10) and (channel_id=0 or channel_id is null)

149 (65.088272094727): SELECT livesite FROM jos_dp_categories WHERE id=10 AND published='1' LIMIT 1

150 (72.002410888672): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294797105 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294797105 AND published='1' LIMIT 1

151 (42.915344238281): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294797105 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294797105 AND published='1' LIMIT 1

152 (38.862228393555): select jos_twitters.link from jos_twitters where cat=10

153 (30.994415283203): select jos_facebook.link from jos_facebook where cat=10

154 (30.994415283203): select jos_google_plus.link from jos_google_plus where cat=10

155 (33.140182495117): select jos_linkedin.link from jos_linkedin where cat=10

156 (262.02201843262): update jos_bannersmanager_banner set impmade=impmade+1 where id in(14615,14202,14203)

157 (!!!!! 1504.1828155518): insert into jos_banners_delta values (14615,'2025-04-29 15:48:58','18.222.24.251','view'),(14202,'2025-04-29 15:48:58','18.222.24.251','view'),(14203,'2025-04-29 15:48:58','18.222.24.251','view')

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