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AI Solution Provides Radiologists with 'Second Pair' Of Eyes to Detect Breast Cancers

By MedImaging International staff writers
Posted on 22 Feb 2024

Mammography, a key tool in breast cancer screening, has proven effective in improving patient outcomes and reducing mortality by identifying breast cancers at an earlier, more manageable stage. Despite its effectiveness, it's estimated that 20-30% of interval cancers, which should have been detected during the previous mammogram, are missed. Additionally, many suspicious findings are ultimately found to be benign. To enhance sensitivity in detecting disease, European guidelines recommend that two radiologists independently review each screening mammogram. However, there's a notable shortage of breast radiologists globally, and training a radiologist to proficiently interpret mammograms can take more than a decade. In response to these challenges, Artificial Intelligence (AI) has been suggested as a potential automated second reviewer for mammograms. This could not only reduce the radiologists' workload but also enhance screening accuracy. AI has shown promising results in retrospective studies, where it was used to decide whether mammogram examinations should be read by one or two radiologists, and in providing radiologists with computer-aided detection (CAD) markings to highlight suspicious areas, thereby reducing the incidence of false negatives. Now, an advanced AI solution provides radiologists with a 'second pair' of eyes to help detect cancers earlier and reduce recall rates.

ScreenPoint Medical’s (Nijmegen, Netherlands) Transpara breast AI is designed to assist radiologists in the early detection of breast cancers and enhance the efficiency of breast screening programs. Utilized by numerous leading institutions across over 30 countries, Transpara is integrated into the radiologists' workflow. Studies have shown that Transpara can identify up to 45% of interval cancers earlier, while also reducing the workload and optimizing workflow processes. Transpara demonstrates consistent performance across various countries, patient ages, breast densities, and ethnic backgrounds. To date, Transpara breast AI has analyzed over five million mammograms, including more than one million Tomosynthesis (3D) exams, supporting radiologists in mammography examinations. The system has received FDA clearance and European regulatory approval (CE Mark) for use with both 2D and 3D mammography from multiple manufacturers.

Transpara continues to deliver proven clinical and workflow benefits in mammography screening in global practice and clinical research. A first-of-its-kind randomized controlled trial, the MASAI-trial, investigated cancer detection rates and the types of cancers detected using AI-supported screening. This trial found notable improvements in cancer detection when AI support was used, compared to traditional double reading methods without AI. Another prospective clinical trial explored the use of AI in safely reducing the radiologists' workload. It focused on using AI to exclude low-risk cases from human review and applying double reading to the remaining cases.

"We are glad that users and researchers continue to see value from Transpara in improving the mammography screening process,” said Mark Koeniguer, ScreenPoint Medical CEO. “It's important to note that these studies reflect global consistency in Transpara's performance. In fact, we now have retrospective, prospective and randomized controlled trials all showing that Transpara provides radiologists with the ability to effectively detect cancer early while keeping recall rates consistent. Women should not have to compromise."

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84 (56.982040405273): SELECT show_live FROM jos_com_show_setting LIMIT 1

85 (!!!!! 4397.1538543701): SELECT show_live FROM jos_com_show_setting LIMIT 1

86 (118.97087097168): SELECT show_live FROM jos_com_show_setting LIMIT 1

87 (51.021575927734): SELECT show_live FROM jos_com_show_setting LIMIT 1

88 (40.054321289062): SELECT show_live FROM jos_com_show_setting LIMIT 1

89 (50.067901611328): SELECT show_live FROM jos_com_show_setting LIMIT 1

90 (39.100646972656): SELECT show_live FROM jos_com_show_setting LIMIT 1

91 (142.09747314453): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294800345 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294800345 AND published='1' LIMIT 1

92 (52.928924560547): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294800345 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294800345 AND published='1' LIMIT 1

93 (219.10667419434): SELECT dp.*, ch.title as channel, exp.name as author_name, exp.specialization as author_specialization, exp.images as author_photo FROM jos_deeppockets as dp LEFT JOIN jos_experts as exp ON exp.id = dp.author LEFT JOIN jos_deeppockets as ch ON dp.fid = ch.id WHERE 1=1 AND dp.cat=10 AND dp.id=294800345 AND (dp.type='deeppockets_item' OR dp.type='deeppockets_item_link') AND dp.published='1' LIMIT 1

94 (204.08630371094): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294800345 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294800345 AND published='1' LIMIT 1

95 (!!!!! 4046.9169616699): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294800345 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294800345 AND published='1' LIMIT 1

96 (496.14906311035): SELECT dp.*, ch.title as channel, exp.name as author_name, exp.specialization as author_specialization, exp.images as author_photo FROM jos_deeppockets as dp LEFT JOIN jos_experts as exp ON exp.id = dp.author LEFT JOIN jos_deeppockets as ch ON dp.fid = ch.id WHERE 1=1 AND dp.id=294800345 AND (dp.type='deeppockets_item' OR dp.type='deeppockets_item_link') AND dp.published='1' LIMIT 1

97 (597.00012207031): SELECT dp.name, dp.id, dp2.name as channel, ex.name as author_name, ex.specialization, ex.images FROM jos_deeppockets as dp LEFT JOIN jos_experts as ex ON ex.id = dp.author LEFT JOIN jos_deeppockets as dp2 ON dp2.id = dp.fid WHERE dp.author != 0 AND dp.cat = 10 AND dp.published = 1 AND ( (dp.fid = 294743300) OR (dp.fid = 294743301) OR (dp.fid = 294743302) OR (dp.fid = 294743303) OR (dp.fid = 294743304) OR (dp.fid = 294743305) OR (dp.fid = 294743306) OR (dp.fid = 294743307) OR (dp.fid = 294743308) OR (dp.fid = 294743309) OR (dp.fid = 294743310) ) ORDER BY RAND() LIMIT 1

98 (385.99967956543): SELECT dp.name, dp.id, dp2.name as channel, ex.name as author_name, ex.specialization, ex.images FROM jos_deeppockets as dp LEFT JOIN jos_experts as ex ON ex.id = dp.author LEFT JOIN jos_deeppockets as dp2 ON dp2.id = dp.fid WHERE dp.author != 0 AND dp.cat = 10 AND dp.published = 1 AND ( (dp.fid = 294743300) OR (dp.fid = 294743301) OR (dp.fid = 294743302) OR (dp.fid = 294743303) OR (dp.fid = 294743304) OR (dp.fid = 294743305) OR (dp.fid = 294743306) OR (dp.fid = 294743307) OR (dp.fid = 294743308) OR (dp.fid = 294743309) OR (dp.fid = 294743310) ) ORDER BY RAND() LIMIT 1

99 (97.036361694336): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294800345 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294800345 AND published='1' LIMIT 1

100 (46.968460083008): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294800345 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294800345 AND published='1' LIMIT 1

101 (129.93812561035): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294800345 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294800345 AND published='1' LIMIT 1

102 (56.028366088867): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294800345 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294800345 AND published='1' LIMIT 1

103 (72.002410888672): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294800345 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294800345 AND published='1' LIMIT 1

104 (41.007995605469): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294800345 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294800345 AND published='1' LIMIT 1

105 (338.07754516602): SELECT * FROM trending_articles WHERE `journal_id` = 10 AND `timestamp` <= NOW() + INTERVAL 7 DAY ORDER BY `order`

106 (!!!!! 55989.027023315): SELECT * FROM jos_deeppockets WHERE jos_deeppockets.cat = 10 AND jos_deeppockets.type = 'deeppockets_item' AND jos_deeppockets.published = 1 AND jos_deeppockets.created + INTERVAL 14 DAY >= NOW() ORDER BY jos_deeppockets.hits DESC LIMIT 7

107 (102.04315185547): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294800345 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294800345 AND published='1' LIMIT 1

108 (46.968460083008): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294800345 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294800345 AND published='1' LIMIT 1

109 (473.97613525391): SELECT fid FROM jos_deeppockets WHERE cat=10 AND id=294800345 AND type='deeppockets_item' AND published='1' union SELECT fid FROM jos_deeppockets_archive WHERE cat=10 AND id=294800345 AND type='deeppockets_item' AND published='1' LIMIT 1

110 (!!!!! 753278.01704407): ( SELECT dp.id, dp.name, dp.title, dp.video, dp.video_source, dp.created FROM jos_deeppockets AS dp WHERE dp.video != '' AND dp.video_source != '' AND dp.cat = 10 AND dp.published = 1 AND dp.type != 'deeppockets_item_link' ORDER BY created DESC LIMIT 3 ) UNION ( SELECT dpa.id, dpa.name, dpa.title, dpa.video, dpa.video_source, dpa.created FROM jos_deeppockets_archive AS dpa WHERE dpa.video != '' AND dpa.video_source != '' AND dpa.cat = 10 AND dpa.published = 1 AND dpa.type != 'deeppockets_item_link' ORDER BY created DESC LIMIT 3 ) ORDER BY created DESC LIMIT 3

111 (107.0499420166): ( SELECT dp.id, dp.name, dp.title, dp.video, dp.video_source, dp.created FROM jos_deeppockets AS dp WHERE dp.video != '' AND dp.video_source != '' AND dp.cat = 10 AND dp.published = 1 AND dp.type != 'deeppockets_item_link' ORDER BY created DESC LIMIT 3 ) UNION ( SELECT dpa.id, dpa.name, dpa.title, dpa.video, dpa.video_source, dpa.created FROM jos_deeppockets_archive AS dpa WHERE dpa.video != '' AND dpa.video_source != '' AND dpa.cat = 10 AND dpa.published = 1 AND dpa.type != 'deeppockets_item_link' ORDER BY created DESC LIMIT 3 ) ORDER BY created DESC LIMIT 3

112 (359.05838012695): SELECT dp.id, dp.name, dp.title, dp.video, dp.video_source, dp.created FROM jos_deeppockets AS dp WHERE dp.id = 294800513 LIMIT 1

113 (81.777572631836): SELECT dp.id, dp.name, dp.title, dp.video, dp.video_source, dp.created FROM jos_deeppockets AS dp WHERE dp.id = 294800513 LIMIT 1

114 (313.04359436035): SELECT dp.id, dp.name, dp.title, dp.video, dp.video_source, dp.created FROM jos_deeppockets AS dp WHERE dp.id = 294800359 LIMIT 1

115 (55.789947509766): SELECT dp.id, dp.name, dp.title, dp.video, dp.video_source, dp.created FROM jos_deeppockets AS dp WHERE dp.id = 294800359 LIMIT 1

116 (231.02760314941): SELECT dp.id, dp.name, dp.title, dp.video, dp.video_source, dp.created FROM jos_deeppockets AS dp WHERE dp.id = 294800361 LIMIT 1

117 (46.014785766602): SELECT dp.id, dp.name, dp.title, dp.video, dp.video_source, dp.created FROM jos_deeppockets AS dp WHERE dp.id = 294800361 LIMIT 1

118 (502.10952758789): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294800345 AND (type='deeppockets_item' OR type='deeppockets_item_link') AND published='1' LIMIT 1

119 (252.00843811035): SELECT name FROM jos_deeppockets WHERE id=211

120 (36.001205444336): SELECT name FROM jos_deeppockets WHERE id=211

121 (484.94338989258): SELECT *, DATE_FORMAT(publish_up,'%d %b %Y') AS date_publish_up, DATE_FORMAT(publish_down,'%d %b %Y') AS date_publish_down FROM jos_events WHERE state=1 AND publish_up > NOW() and extra_info REGEXP '((;)|(^))211((;)|($))' AND catid IN (0,110) ORDER BY publish_up ASC LIMIT 3

122 (338.79280090332): SELECT *, DATE_FORMAT(publish_up,'%d %b %Y') AS date_publish_up, DATE_FORMAT(publish_down,'%d %b %Y') AS date_publish_down FROM jos_events WHERE state=1 AND publish_up > NOW() and extra_info REGEXP '((;)|(^))211((;)|($))' AND catid IN (0,110) ORDER BY publish_up ASC LIMIT 3

123 (57.93571472168): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294800345 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294800345 AND published='1' LIMIT 1

124 (45.061111450195): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294800345 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294800345 AND published='1' LIMIT 1

125 (!!!!! 11643.886566162): TRUNCATE TABLE jos_trademed_module

126 (117.06352233887): SELECT dp.*, ch.title as channel, exp.name as author_name, exp.specialization as author_specialization, exp.images as author_photo FROM jos_deeppockets as dp LEFT JOIN jos_experts as exp ON exp.id = dp.author LEFT JOIN jos_deeppockets as ch ON dp.fid = ch.id WHERE 1=1 AND dp.cat=10 AND dp.id=294800345 AND (dp.type='deeppockets_item' OR dp.type='deeppockets_item_link') AND dp.published='1' LIMIT 1

127 (669.95620727539): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294800345 AND (type='deeppockets_item' OR type='deeppockets_item_link') AND published='1' LIMIT 1

128 (94.175338745117): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294800345 AND (type='deeppockets_item' OR type='deeppockets_item_link') AND published='1' LIMIT 1

129 (169.03877258301): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294800345 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294800345 AND published='1' LIMIT 1

130 (77.962875366211): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294800345 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294800345 AND published='1' LIMIT 1

131 (!!!!! 1665.1153564453): SELECT jos_item.* FROM jos_item INNER JOIN jos_number ON jos_item.numberID=jos_number.id WHERE 1=1 AND (jos_item.imgMini<>'') AND jos_item.type='L' AND jos_item.numberID= ( SELECT jos_number.id FROM jos_number WHERE jos_number.journalID IN (10) and jos_number.id in (select distinct jos_number.id from jos_number join jos_item on jos_item.numberid=jos_number.id where jos_item.type='P') ORDER BY (CONVERT(SUBSTRING(issue,1,2),SIGNED) + (CONVERT(SUBSTRING(issue,3,2),SIGNED)*100)) DESC LIMIT 0,1 ) ORDER BY RAND() DESC LIMIT 6

132 (90.837478637695): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294800345 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294800345 AND published='1' LIMIT 1

133 (84.877014160156): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294800345 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294800345 AND published='1' LIMIT 1

134 (66.995620727539): SELECT fid FROM jos_deeppockets WHERE cat=10 AND id=294800345 AND type='deeppockets_item' AND published='1' union SELECT fid FROM jos_deeppockets_archive WHERE cat=10 AND id=294800345 AND type='deeppockets_item' AND published='1' LIMIT 1

135 (50.067901611328): select distinct links.* from jos_textlinks links join jos_textlinks_placement placement on links.id=placement.link_id where journal_id=(10) and (channel_id=211 or channel_id is null)

136 (68.187713623047): select distinct links.* from jos_textlinks links join jos_textlinks_placement placement on links.id=placement.link_id where journal_id=(10) and (channel_id=211 or channel_id is null)

137 (61.988830566406): SELECT livesite FROM jos_dp_categories WHERE id=10 AND published='1' LIMIT 1

138 (100.13580322266): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294800345 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294800345 AND published='1' LIMIT 1

139 (76.055526733398): SELECT * FROM jos_deeppockets WHERE 1=1 AND id=294800345 AND published='1' union SELECT * FROM jos_deeppockets_archive WHERE 1=1 AND id=294800345 AND published='1' LIMIT 1

140 (196.93374633789): select jos_twitters.link from jos_twitters where cat=10

141 (44.107437133789): select jos_facebook.link from jos_facebook where cat=10

142 (43.153762817383): select jos_google_plus.link from jos_google_plus where cat=10

143 (30.994415283203): select jos_linkedin.link from jos_linkedin where cat=10

144 (331.16340637207): update jos_bannersmanager_banner set impmade=impmade+1 where id in(14615,14202,14203)

145 (!!!!! 1491.0697937012): insert into jos_banners_delta values (14615,'2025-04-29 16:29:15','18.223.109.25','view'),(14202,'2025-04-29 16:29:15','18.223.109.25','view'),(14203,'2025-04-29 16:29:15','18.223.109.25','view')

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